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Upregulation of Trem2 expression occurs exclusively on microglial contact with plaques
View ORCID ProfileJack Wood, Eugenia Wong, Ridwaan Joghee, Aya Balbaa, View ORCID ProfileKarina S. Vitanova, Alison Vanshoiack, Stefan-Laural J. Phelan, View ORCID ProfileFrancesca Launchbury, Sneha Desai, View ORCID ProfileTakshashila Tripathi, View ORCID ProfileJörg Hanrieder, View ORCID ProfileDamian M. Cummings, John Hardy, View ORCID ProfileFrances A. Edwards
doi: https://doi.org/10.1101/2022.01.26.477873
Jack Wood
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
5Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
Eugenia Wong
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Ridwaan Joghee
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Aya Balbaa
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Karina S. Vitanova
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Alison Vanshoiack
2Nanostring Technologies, 530 Fairview Ave N, Seattle, WA 98109, United States
Stefan-Laural J. Phelan
2Nanostring Technologies, 530 Fairview Ave N, Seattle, WA 98109, United States
Francesca Launchbury
3Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
Sneha Desai
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Takshashila Tripathi
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Jörg Hanrieder
3Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
5Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
Damian M. Cummings
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
John Hardy
4Dementia Research Institute, University College London, Gower Street, London WC1E 6BT, United Kingdom
3Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
Frances A. Edwards
1Department of Neuroscience, Physiology & Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
6Institute of Healthy Ageing, University College London, Gower Street, London WC1E 6BT, United Kingdom
Article usage
Posted January 28, 2022.
Upregulation of Trem2 expression occurs exclusively on microglial contact with plaques
Jack Wood, Eugenia Wong, Ridwaan Joghee, Aya Balbaa, Karina S. Vitanova, Alison Vanshoiack, Stefan-Laural J. Phelan, Francesca Launchbury, Sneha Desai, Takshashila Tripathi, Jörg Hanrieder, Damian M. Cummings, John Hardy, Frances A. Edwards
bioRxiv 2022.01.26.477873; doi: https://doi.org/10.1101/2022.01.26.477873
Upregulation of Trem2 expression occurs exclusively on microglial contact with plaques
Jack Wood, Eugenia Wong, Ridwaan Joghee, Aya Balbaa, Karina S. Vitanova, Alison Vanshoiack, Stefan-Laural J. Phelan, Francesca Launchbury, Sneha Desai, Takshashila Tripathi, Jörg Hanrieder, Damian M. Cummings, John Hardy, Frances A. Edwards
bioRxiv 2022.01.26.477873; doi: https://doi.org/10.1101/2022.01.26.477873
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