About bioRxiv

bioRxiv (pronounced "bio-archive") is a free online archive and distribution service for unpublished preprints in the life sciences. It is operated by Cold Spring Harbor Laboratory, a not-for-profit research and educational institution. By posting preprints on bioRxiv, authors are able to make their findings immediately available to the scientific community and receive feedback on draft manuscripts before they are submitted to journals.

Articles are not peer-reviewed, edited, or typeset before being posted online. However, all articles undergo a basic screening process for offensive and/or non-scientific content and are checked for plagiarism. No endorsement of an article’s methods, assumptions, conclusions, or scientific quality by Cold Spring Harbor Laboratory is implied by its appearance in bioRxiv. An article may be posted prior to, or concurrently with, submission to a journal but should not be posted if it has already been published.

Authors may submit a revised version of an article to bioRxiv at any time (prior to publication in a journal). Once posted on bioRxiv, articles are citable and therefore cannot be removed.


bioRxiv accepts preprints of articles covering all aspects of research in the life sciences. When posting an article, the author assigns it to one of the following categories:

  • Animal Behavior and Cognition
  • Biochemistry
  • Bioengineering
  • Bioinformatics
  • Biophysics
  • Cancer Biology
  • Cell Biology
  • Clinical Trials
  • Developmental Biology
  • Ecology
  • Evolutionary Biology
  • Genetics
  • Genomics
  • Immunology
  • Microbiology
  • Molecular Biology
  • Neuroscience
  • Paleontology
  • Pathology
  • Pharmacology
  • Physiology
  • Plant Biology
  • Scientific Communication
  • Synthetic Biology
  • Systems Biology
  • Zoology

Articles in the physical sciences, mathematics, or social sciences should only be posted on bioRxiv if they have direct relevance to the life sciences. Articles in these areas that are not relevant to life sciences should instead be posted on servers such as arXiv, which bioRxiv is intended to complement.


Articles in bioRxiv are categorized as New Results, Confirmatory Results, or Contradictory Results. New Results describe an advance in a field. Confirmatory Results largely replicate and confirm previously published work, whereas Contradictory Results largely replicate experimental approaches used in previously published work but the results contradict and/or do not
support it.

Advisory Board

  • Anurag Acharya
  • Rick Anderson
    (University of Utah)
  • Jonathan Eisen
    (UC Davis)
  • Paul Ginsparg
    (Cornell and arXiv)
  • Eric Green
  • Hopi Hoekstra
  • Leonid Kruglyak
    (UCLA and HHMI)
  • Frank Norman
    (Francis Crick Institute)
  • Bernd Pulverer
  • John Sack
  • Sandra Schmid
    (UT Southwestern)
  • Pamela Silver
  • Eric Topol
    (Scripps Research Institute)
  • Leslie Vosshall
    (Rockefeller University)
  • Fiona Watt
    (King's College London)
  • Mike Wigler
    (Cold Spring Harbor Laboratory)


Preprints deposited in bioRxiv can be cited using their digital object identifier (doi).

Example: Author AN, Author BT. 2013. My article title. bioRxiv doi: 10.1101/123456


Authors retain copyright and choose from several distribution/reuse options under which to make the article available (CC-BY, CC-BY-NC, CC-BY-ND, CC-BY-NC-ND, or no reuse). By posting on bioRxiv, authors explicitly consent to text mining of their work (e.g., by search engines or researchers).

bioRxiv reserves the right to identify and remove any articles that contain plagiarized material or describe experimental work that is not performed in accordance with the relevant ethical standards for research using animals or human subjects.


Once an article is published in a journal, bioRxiv will update the preprint with a link to the published version.


Readers may add public comments to articles on bioRxiv. Comments are moderated to ensure they conform to the standards of normal professional discourse. Readers are also free to contact authors directly.


Most research journals allow posting on preprint servers such as bioRxiv prior to publication. A list of journal policies can be found on Wikipedia and SHERPA/RoMEO. Authors should consult these lists and other sources of information before posting on bioRxiv.

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