New Results
Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro
B. Mossink, A.H.A. Verboven, E.J.H. van Hugte, T.M. Klein Gunnewiek, G. Parodi, K. Linda, C. Schoenmaker, T. Kleefstra, T. Kozicz, H. van Bokhoven, D. Schubert, N. Nadif Kasri, M. Frega
doi: https://doi.org/10.1101/2021.01.20.427439
B. Mossink
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
A.H.A. Verboven
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
2Centre for Molecular and Biomolecular Informatics, Radboudumc, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, the Netherlands
E.J.H. van Hugte
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
3ACE Kempenhaeghe, Department of Epileptology, 5591 VE Heeze, the Netherlands
T.M. Klein Gunnewiek
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
4Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands
G. Parodi
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
K. Linda
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
C. Schoenmaker
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
T. Kleefstra
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
T. Kozicz
4Department of Medical Imaging, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands
5Department of Laboratory Medicine and Pathology, Mayo Clinic, 55905Rochester, MN, USA
6Department of Clinical Genomics, Mayo Clinic, 55905 Rochester, MN, USA
H. van Bokhoven
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
7Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, 6500 HB Nijmegen, the Netherlands
D. Schubert
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
7Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, 6500 HB Nijmegen, the Netherlands
N. Nadif Kasri
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
7Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, 6500 HB Nijmegen, the Netherlands
M. Frega
1Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, 6500 HB Nijmegen, the Netherlands
6Department of Clinical Genomics, Mayo Clinic, 55905 Rochester, MN, USA
Posted January 21, 2021.
Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro
B. Mossink, A.H.A. Verboven, E.J.H. van Hugte, T.M. Klein Gunnewiek, G. Parodi, K. Linda, C. Schoenmaker, T. Kleefstra, T. Kozicz, H. van Bokhoven, D. Schubert, N. Nadif Kasri, M. Frega
bioRxiv 2021.01.20.427439; doi: https://doi.org/10.1101/2021.01.20.427439
Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro
B. Mossink, A.H.A. Verboven, E.J.H. van Hugte, T.M. Klein Gunnewiek, G. Parodi, K. Linda, C. Schoenmaker, T. Kleefstra, T. Kozicz, H. van Bokhoven, D. Schubert, N. Nadif Kasri, M. Frega
bioRxiv 2021.01.20.427439; doi: https://doi.org/10.1101/2021.01.20.427439
Subject Area
Subject Areas
- Biochemistry (11783)
- Bioengineering (8765)
- Bioinformatics (29249)
- Biophysics (15000)
- Cancer Biology (12136)
- Cell Biology (17441)
- Clinical Trials (138)
- Developmental Biology (9441)
- Ecology (14199)
- Epidemiology (2067)
- Evolutionary Biology (18332)
- Genetics (12259)
- Genomics (16813)
- Immunology (11885)
- Microbiology (28133)
- Molecular Biology (11621)
- Neuroscience (61060)
- Paleontology (452)
- Pathology (1875)
- Pharmacology and Toxicology (3240)
- Physiology (4970)
- Plant Biology (10436)
- Synthetic Biology (2890)
- Systems Biology (7350)
- Zoology (1653)