Article Information
History
- October 29, 2020.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Shijia Liu1,2,
- Dongil Kim1,
- Tae Gyu Oh3,
- Gerald Pao4,
- Jonghyun Kim1,
- Richard D. Palmiter5,
- Matthew R. Banghart2,
- Kuo-Fen Lee1,2,
- Ronald M. Evans3 and
- Sung Han1,2,*
- 1Peptide Biology Laboratories, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
- 2Section of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA
- 3Howard Hughes Medical Institute, Gene Expression Laboratories, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
- 4Molecular and Cellular Biology Laboratories, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
- 5Howard Hughes Medical Institute, Department of Biochemistry, School of Medicine, University of Washington, Seattle, WA 98195, USA
- ↵*Corresponding author: Sung Han, PhD, email: sunghan{at}salk.edu
Author Contributions: S.H. conceived the idea, designed and constructed respiratory monitoring apparatus, and secured funding. S.H. and S.L. designed the experiments and wrote the manuscript with inputs from other authors. S.L. performed most of the experiments. D.K. and J.K. prepared the sample for RiboTag RNA sequencing. T.G.O. analyzed the data from RiboTag RNA sequencing. G.M.P. performed the CCM analysis. R.D.P. provided the Oprm1Cre mouse line. M.R.B. provided the hMOR virus. K.F.L. and R.M.E. provided experimental resources.