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Mapping the Conformational Landscape of a Dynamic Enzyme by Multitemperature and XFEL Crystallography
Daniel A. Keedy, Lillian R. Kenner, Matthew Warkentin, Rahel A. Woldeyes, Jesse B. Hopkins, Michael C. Thompson, Aaron S. Brewster, Andrew H. Van Benschoten, Elizabeth L. Baxter, Monarin Uervirojnangkoorn, Scott E. McPhillps, Jinhu Song, Roberto Alonso-Mori, James M. Holton, William I. Weis, Axel T. Brunger, S. Michael Soltis, Henrik Lemke, Ana Gonzalez, Nicholas K. Sauter, Aina E. Cohen, Henry van den Bedem, Robert E. Thorne, View ORCID ProfileJames S. Fraser
doi: https://doi.org/10.1101/016733
Daniel A. Keedy
1Dept. of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158
Lillian R. Kenner
1Dept. of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158
Matthew Warkentin
2Physics Dept., Cornell University, Ithaca, NY 14853
Rahel A. Woldeyes
1Dept. of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158
Jesse B. Hopkins
2Physics Dept., Cornell University, Ithaca, NY 14853
Michael C. Thompson
1Dept. of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158
Aaron S. Brewster
3Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720
Andrew H. Van Benschoten
1Dept. of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158
Elizabeth L. Baxter
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Monarin Uervirojnangkoorn
5Dept. of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305
6Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305
Scott E. McPhillps
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Jinhu Song
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Roberto Alonso-Mori
7Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
James M. Holton
3Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
8Dept. of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158
William I. Weis
5Dept. of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305
9Dept. of Structural Biology, Stanford University, Stanford, CA 94305
10Dept. of Photon Sciences, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Axel T. Brunger
5Dept. of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305
6Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305
9Dept. of Structural Biology, Stanford University, Stanford, CA 94305
10Dept. of Photon Sciences, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
S. Michael Soltis
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Henrik Lemke
7Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Ana Gonzalez
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Nicholas K. Sauter
3Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720
Aina E. Cohen
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Henry van den Bedem
4Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025
Robert E. Thorne
2Physics Dept., Cornell University, Ithaca, NY 14853
James S. Fraser
1Dept. of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158
Article usage
Posted August 29, 2015.
Mapping the Conformational Landscape of a Dynamic Enzyme by Multitemperature and XFEL Crystallography
Daniel A. Keedy, Lillian R. Kenner, Matthew Warkentin, Rahel A. Woldeyes, Jesse B. Hopkins, Michael C. Thompson, Aaron S. Brewster, Andrew H. Van Benschoten, Elizabeth L. Baxter, Monarin Uervirojnangkoorn, Scott E. McPhillps, Jinhu Song, Roberto Alonso-Mori, James M. Holton, William I. Weis, Axel T. Brunger, S. Michael Soltis, Henrik Lemke, Ana Gonzalez, Nicholas K. Sauter, Aina E. Cohen, Henry van den Bedem, Robert E. Thorne, James S. Fraser
bioRxiv 016733; doi: https://doi.org/10.1101/016733
Mapping the Conformational Landscape of a Dynamic Enzyme by Multitemperature and XFEL Crystallography
Daniel A. Keedy, Lillian R. Kenner, Matthew Warkentin, Rahel A. Woldeyes, Jesse B. Hopkins, Michael C. Thompson, Aaron S. Brewster, Andrew H. Van Benschoten, Elizabeth L. Baxter, Monarin Uervirojnangkoorn, Scott E. McPhillps, Jinhu Song, Roberto Alonso-Mori, James M. Holton, William I. Weis, Axel T. Brunger, S. Michael Soltis, Henrik Lemke, Ana Gonzalez, Nicholas K. Sauter, Aina E. Cohen, Henry van den Bedem, Robert E. Thorne, James S. Fraser
bioRxiv 016733; doi: https://doi.org/10.1101/016733
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