[HTML][HTML] Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

…, M Beltramello, AC Walls, MA Tortorici, S Bianchi… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly emerged
coronavirus that is responsible for the current pandemic of coronavirus disease 2019 (COVID-19), …

[HTML][HTML] Sensitivity of SARS-CoV-2 B. 1.1. 7 to mRNA vaccine-elicited antibodies

…, SA Kemp, J Bassi, D Pinto, C Silacci-Fregni, S Bianchi… - Nature, 2021 - nature.com
Transmission of SARS-CoV-2 is uncontrolled in many parts of the world; control is compounded
in some areas by the higher transmission potential of the B.1.1.7 variant 1 , which has …

SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern

…, KR Sprouse, M Agostini, D Pinto, K Culap, S Bianchi… - Science, 2021 - science.org
A novel variant of concern (VOC) named CAL.20C (B.1.427/B.1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide, W152C …

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

…, BM Fernandez-Rodriguez, G Agatic, S Bianchi… - Science, 2011 - science.org
The isolation of broadly neutralizing antibodies against influenza A viruses has been a long-sought
goal for therapeutic approaches and vaccine design. Using a single-cell culture …

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

…, S Jaconi, F Zatta, A De Marco, B Guarino, S Bianchi… - Science, 2020 - science.org
Efficient therapeutic options are needed to control the spread of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) that has caused more than 922,000 fatalities as of 13 …

[PDF][PDF] N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2

…, M Montiel-Ruiz, J Zhou, LE Rosen, S Bianchi… - Cell, 2021 - cell.com
The SARS-CoV-2 spike (S) glycoprotein contains an immunodominant receptor-binding
domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient plasma. Little …

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

…, DA Espinosa, V Graham, A Cassotta, S Bianchi… - Science, 2016 - science.org
Zika virus (ZIKV), a mosquito-borne flavivirus with homology to Dengue virus (DENV), has
become a public health emergency. By characterizing memory lymphocytes from ZIKV-…

Broad betacoronavirus neutralization by a stem helix–specific human antibody

…, R Abdelnabi, C Foo, L Coelmont, I Bartha, S Bianchi… - Science, 2021 - science.org
The spillovers of betacoronaviruses in humans and the emergence of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for broad coronavirus …

[HTML][HTML] Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies

…, F Benigni, J Noack, YJ Park, S Bianchi… - Nature, 2021 - nature.com
SARS-CoV-2 infection—which involves both cell attachment and membrane fusion—relies
on the angiotensin-converting enzyme 2 (ACE2) receptor, which is paradoxically found at low …

[PDF][PDF] Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication

…, MH Verheije, T Calì, M Ulasli, S Bianchi… - Cell host & …, 2010 - cell.com
Coronaviruses (CoV), including SARS and mouse hepatitis virus (MHV), are enveloped
RNA viruses that induce formation of double-membrane vesicles (DMVs) and target their …