Autophagy in major human diseases
Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
Diverse applications of nanomedicine
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …
health-related issues continues to receive increasing interest. Research in nanomedicine …
Molecular definitions of autophagy and related processes
Over the past two decades, the molecular machinery that underlies autophagic responses
has been characterized with ever increasing precision in multiple model organisms. Moreover…
has been characterized with ever increasing precision in multiple model organisms. Moreover…
[HTML][HTML] Genomic variation in 3,010 diverse accessions of Asian cultivated rice
Here we analyse genetic variation, population structure and diversity among 3,010 diverse
Asian cultivated rice (Oryza sativa L.) genomes from the 3,000 Rice Genomes Project. Our …
Asian cultivated rice (Oryza sativa L.) genomes from the 3,000 Rice Genomes Project. Our …
[HTML][HTML] The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes
…, I Bancroft, TJ Yang, Q Hu, X Wang, Z Yue… - Nature …, 2014 - nature.com
Polyploidization has provided much genetic variation for plant adaptive evolution, but the
mechanisms by which the molecular evolution of polyploid genomes establishes genetic …
mechanisms by which the molecular evolution of polyploid genomes establishes genetic …
[HTML][HTML] The draft genome of a diploid cotton Gossypium raimondii
K Wang, Z Wang, F Li, W Ye, J Wang, G Song, Z Yue… - Nature …, 2012 - nature.com
We have sequenced and assembled a draft genome of G. raimondii, whose progenitor is
the putative contributor of the D subgenome to the economically important fiber-producing …
the putative contributor of the D subgenome to the economically important fiber-producing …
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
Z Yue, S Jin, C Yang, AJ Levine… - Proceedings of the …, 2003 - National Acad Sciences
The biochemical properties of beclin 1 suggest a role in two fundamentally important cell
biological pathways: autophagy and apoptosis. We show here that beclin 1 -/- mutant mice die …
biological pathways: autophagy and apoptosis. We show here that beclin 1 -/- mutant mice die …
[HTML][HTML] Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
Inactivation of constitutive autophagy results in formation of cytoplasmic protein inclusions
and leads to liver injury and neurodegeneration, but the details of abnormalities related to …
and leads to liver injury and neurodegeneration, but the details of abnormalities related to …
[HTML][HTML] Genome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential
Foxtail millet (Setaria italica), a member of the Poaceae grass family, is an important food and
fodder crop in arid regions and has potential for use as a C 4 biofuel. It is a model system …
fodder crop in arid regions and has potential for use as a C 4 biofuel. It is a model system …
Surface charge affects cellular uptake and intracellular trafficking of chitosan-based nanoparticles
Chitosan-based nanoparticles (NPs) are widely used in drug delivery, device-based therapy,
tissue engineering, and medical imaging. In this aspect, a clear understanding of how …
tissue engineering, and medical imaging. In this aspect, a clear understanding of how …