User profiles for Z. Cader
Zameel CaderProfessor of Neuroscience and Neurology, Oxford University Verified email at ndcn.ox.ac.uk Cited by 7684 |
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Migraine is a debilitating neurological disorder affecting around one in seven people worldwide,
but its molecular mechanisms remain poorly understood. There is some debate about …
but its molecular mechanisms remain poorly understood. There is some debate about …
[PDF][PDF] GM-CSF calibrates macrophage defense and wound healing programs during intestinal infection and inflammation
…, JR Ferdinand, K Harcourt, BJ Stewart, Z Cader… - Cell reports, 2020 - cell.com
Macrophages play a central role in intestinal immunity, but inappropriate macrophage
activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-…
activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-…
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis
…, GD Banham, RJ Mathews, Z Cader… - Proceedings of the …, 2020 - National Acad Sciences
IgG antibodies cause inflammation and organ damage in autoimmune diseases such as
systemic lupus erythematosus (SLE). We investigated the metabolic profile of macrophages …
systemic lupus erythematosus (SLE). We investigated the metabolic profile of macrophages …
[HTML][HTML] Functional analysis of missense variants in the TRESK (KCNK18) K+ channel
A loss of function mutation in the TRESK K2P potassium channel (KCNK18), has recently
been linked with typical familial migraine with aura. We now report the functional …
been linked with typical familial migraine with aura. We now report the functional …
Mitophagy and Alzheimer's disease: cellular and molecular mechanisms
Neurons affected in Alzheimer's disease (AD) experience mitochondrial dysfunction and a
bioenergetic deficit that occurs early and promotes the disease-defining amyloid beta peptide (…
bioenergetic deficit that occurs early and promotes the disease-defining amyloid beta peptide (…
Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation
MZ Cader, A Kaser - Gut, 2013 - gut.bmj.com
The intestine and its immune system have evolved to meet the extraordinary task of maintaining
tolerance to the largest, most complex and diverse microbial commensal habitat, while …
tolerance to the largest, most complex and diverse microbial commensal habitat, while …
Significant linkage to migraine with aura on chromosome 11q24
… The markers with scores greater than LOD=1.0 are listed in Table 1 and Figure 1 shows the
maximum LOD score ( Z max ) for each marker across the genome. The highest LOD score …
maximum LOD score ( Z max ) for each marker across the genome. The highest LOD score …
The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development
…, L Pickup, P Nightingale, G Allen, Z Cader… - …, 2018 - academic.oup.com
Objectives Tenosynovitis (TS) is common in early arthritis. However, the value of US-defined
TS in predicting RA development is unclear. We assessed the predictive utility of US-…
TS in predicting RA development is unclear. We assessed the predictive utility of US-…
Immunotherapy-responsive chorea as the presenting feature of LGI1-antibody encephalitis
… Cader report no disclosures. A. Vincent has received support from and/or has served as
a paid … Baker, and Z. Cader interpreted data. A. Vincent supervised the immunology and …
a paid … Baker, and Z. Cader interpreted data. A. Vincent supervised the immunology and …
Habitual sleep disturbances and migraine: a Mendelian randomization study
… Z scores for heritability were all greater than 4 19 , supporting the validity of genetic … Lee
31−33 , Cynthia Sandor 71 , Caleb Webber 71 , Zameel Cader 72,73 , Bertram Muller-Myhsok 74…
31−33 , Cynthia Sandor 71 , Caleb Webber 71 , Zameel Cader 72,73 , Bertram Muller-Myhsok 74…