User profiles for Y. Pichugin
Yuriy PichuginPrinceton University Verified email at princeton.edu Cited by 286 |
[HTML][HTML] The evolutionary dynamics of extrachromosomal DNA in human cancers
Oncogene amplification on extrachromosomal DNA (ecDNA) is a common event, driving
aggressive tumor growth, drug resistance and shorter survival. Currently, the impact of …
aggressive tumor growth, drug resistance and shorter survival. Currently, the impact of …
[PDF][PDF] Parameters estimation in mechanism design
Y Pichugin, G Alferov, O Malafeyev - 2016 - dspace.spbu.ru
… rect measurements vector Y with a linear regression connection Y = XΘ + ε is also possible.
… Pichugin, Geometrical aspects of testing the complex statistical hypothesis in mathematical …
… Pichugin, Geometrical aspects of testing the complex statistical hypothesis in mathematical …
[PDF][PDF] Statistical estimation of corruption indicators in the firm
O Malafeyev, Y Pichugin - 2016 - dspace.spbu.ru
A new statistical procedure of anti-corruption control of economic activity is proposed in the
paper. The task of the firm's corruption checking is formulated in terms of statistical …
paper. The task of the firm's corruption checking is formulated in terms of statistical …
A statistical method for corrupt agents detection
YA Pichugin, OA Malafeyev, D Rylow… - AIP Conference …, 2018 - pubs.aip.org
… Both matrices Y and N are m × J dimensional. Assume that matrices N and Y do not contain
… q, where yl is a component of the vector y with index l; the order of components is preserved. …
… q, where yl is a component of the vector y with index l; the order of components is preserved. …
[HTML][HTML] Fragmentation modes and the evolution of life cycles
Reproduction is a defining feature of living systems. To reproduce, aggregates of biological
units (eg, multicellular organisms or colonial bacteria) must fragment into smaller parts. …
units (eg, multicellular organisms or colonial bacteria) must fragment into smaller parts. …
Meta‐population structure and the evolutionary transition to multicellularity
The evolutionary transition to multicellularity has occurred on numerous occasions, but
transitions to complex life forms are rare. Here, using experimental bacterial populations as …
transitions to complex life forms are rare. Here, using experimental bacterial populations as …
Cryopreservation of rat hippocampal slices by vitrification
Y Pichugin, GM Fahy, R Morin - Cryobiology, 2006 - Elsevier
Although much interest has attended the cryopreservation of immature neurons for subsequent
therapeutic intracerebral transplantation, there are no reports on the cryopreservation of …
therapeutic intracerebral transplantation, there are no reports on the cryopreservation of …
An environmentally induced multicellular life cycle of a unicellular cyanobacterium
Understanding the evolutionary transition to multicellularity is a key problem in biology.
Nevertheless, the ecological conditions driving such transitions are not well understood. The first …
Nevertheless, the ecological conditions driving such transitions are not well understood. The first …
Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers
The foundational principles of Darwinian evolution are variation, selection, and identity by
descent. Oncogene amplification on extrachromosomal DNA (ecDNA) is a common event, …
descent. Oncogene amplification on extrachromosomal DNA (ecDNA) is a common event, …
Why is cyclic dominance so rare?
… y and z mutations happen leading the emergence of type j and k from the type n respectively.
If y … where x and y indicate the averages of the variables x and y. The index i runs over all …
If y … where x and y indicate the averages of the variables x and y. The index i runs over all …