[HTML][HTML] Live imaging of muscle histolysis in Drosophila metamorphosis

Y Kuleesha, WC Puah, M Wasser - BMC Developmental Biology, 2016 - Springer
Background The contribution of programmed cell death (PCD) to muscle wasting disorders
remains a matter of debate. Drosophila melanogaster metamorphosis offers the opportunity …

A model of muscle atrophy based on live microscopy of muscle remodelling in Drosophila metamorphosis

Y Kuleesha, WC Puah… - Royal Society open …, 2016 - royalsocietypublishing.org
Genes controlling muscle size and survival play important roles in muscle wasting diseases.
In Drosophila melanogaster metamorphosis, larval abdominal muscles undergo two …

[HTML][HTML] FMAj: a tool for high content analysis of muscle dynamics in Drosophila metamorphosis

Y Kuleesha, WC Puah, F Lin, M Wasser - BMC bioinformatics, 2014 - Springer
Background During metamorphosis in Drosophila melanogaster, larval muscles undergo
two different developmental fates; one population is removed by cell death, while the other …

FMAj: a tool for high content analysis of muscle dynamics in Drosophila metamorphosis

WC Puah, Y Kuleesha, F Lin, M Wasser - 2015 - dr.ntu.edu.sg
Background: During metamorphosis in Drosophila melanogaster, larval muscles undergo
two different developmental fates; one population is removed by cell death, while the other …

[HTML][HTML] Spatial pattern analysis of nuclear migration in remodelled muscles during Drosophila metamorphosis

Kuleesha, L Feng, M Wasser - BMC bioinformatics, 2017 - Springer
… Next, we translate the image at time point t horizontally by x pixels and vertically by y pixels,
so that the nuclei at time point t and t + 1 align with each other. This alignment facilitates the …

IoT applied in data transceiver

JF Tu, CY Chen - Innovation, Communication and Engineering, 2013 - books.google.com
This paper, we exploit the Internet-of-Thing (IoT) manner to design a body medicine data
transceiver (BMDT) that iscomposed of 4 parts: 1) the core is a embedded signal chip, 2) three …

Muscle segmentation in time series images of Drosophila metamorphosis

K Yadav, F Lin, M Wasser - 2015 37th Annual International …, 2015 - ieeexplore.ieee.org
In order to study genes associated with muscular disorders, we characterize the phenotypic
changes in Drosophila muscle cells during metamorphosis caused by genetic perturbations. …

Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development

JT Gunderson, AE Peppriell, D Vorojeikina… - Archives of …, 2020 - Springer
… Our results support prior work which showed a DIOM dysmorphology that did not impact
eclosion (Kuleesha et al. 2016a). Further studies are required to understand the purpose of the …

Integration of proteomic and genetic approaches to assess developmental muscle atrophy

DS Brooks, K Vishal, S Bawa, A Alder… - Journal of …, 2021 - journals.biologists.com
… knockdown of Rheb or Tor enhanced DIOM atrophy, while a reduction of the negative
regulators Tsc1 and Tsc2 resulted in larger muscles that failed to undergo atrophy (Kuleesha et al., …

Incidence and risk factors for non‐alcoholic fatty liver disease: A 7‐year follow‐up study among urban, adult Sri Lankans

MA Niriella, A Pathmeswaran, ST De Silva… - Liver …, 2017 - Wiley Online Library
Background This study investigated incidence and risk factors for NAFLD among an adult
cohort with 7‐year follow‐up. Methods The study population (age‐stratified random sampling, …