Proteins provide the basis for cellular function. Having multiple versions of the same protein
within a single organism provides a way of regulating its activity or developing novel …

… (B) Distribution of sideway extension of LH–NL ( δ Y ) in the mutant and WT simulation,
where δ Y = ( r → L H T 338 − r → L H T 326 ) ⋅ e ^ y with e ^ y being the unit vector along the y …

Cytoplasmic dynein, whose motor domain belongs to the AAA+ family, walks on microtubules
toward the minus end. Using the available structures in different nucleotide states, we …

Conventional kinesin, responsible for directional transport of cellular vesicles, takes multiple
nearly uniform 8.2-nm steps by consuming one ATP molecule per step as it walks toward …

… The labels Y and Y′ refer to the residues in the molecules TH, LH, and MT, and X refers to
… Zhechun Zhang, Yonathan Goldtzvik, D. Thirumalai. Parsing the roles of neck-linker docking …

Five small cyclic peptides and four implicit water models, were selected for this study.
DEEPSAM, a structure prediction algorithm built upon TINKER, was used. Structures predicted …

Conventional kinesin, a motor protein that transports cargo within cells, walks by taking
multiple steps toward the plus end of the microtubule (MT). While significant progress has been …

The COVID-19 disease is an ongoing global health concern. Although vaccination provides
some protection, people are still susceptible to re-infection. Ostensibly, certain populations …

The COVID-19 disease is an ongoing global health concern. Although vaccination provides
some protection, people are still susceptible to re-infection. Ostensibly, certain populations …

… Finally and most importantly, I would like to thank my wife, Sharon Goldtzvik, to whom I
believe this thesis belongs just as much as it belongs to me. She has been a constant source of …