The zebrafish's swim to fame as an experimental model in biology
SG Vascotto, Y Beckham… - Biochemistry and cell …, 1997 - cdnsciencepub.com
The zebrafish has long been the favorite organism in many scientific disciplines. Although
its attributes as a model were expounded for many years and thus were no secret, the …
its attributes as a model were expounded for many years and thus were no secret, the …
Tension is required but not sufficient for focal adhesion maturation without a stress fiber template
… of the Rho kinase inhibitor Y-27632. As the concentration of Y-27632 is increased from 1 to
… Cells treated with 1 µM Y-27632 exert traction forces indistinguishable from WT cells. In the …
… Cells treated with 1 µM Y-27632 exert traction forces indistinguishable from WT cells. In the …
Lamellipodium is a myosin-independent mechanosensor
… This study, a culmination of 15 y of research from mice to humans, provides ...Dietary
flavanols are food constituents found in certain fruits and vegetables that have been linked to …
flavanols are food constituents found in certain fruits and vegetables that have been linked to …
Endothelial barrier disruption and recovery is controlled by substrate stiffness
AA Birukova, X Tian, I Cokic, Y Beckham… - Microvascular …, 2013 - Elsevier
Circulating barrier disruptive agonists bind specific cell membrane receptors and trigger signal
transduction pathways leading to the activation of cell contractility and endothelial cell (EC…
transduction pathways leading to the activation of cell contractility and endothelial cell (EC…
[HTML][HTML] Myosin II-mediated focal adhesion maturation is tension insensitive
J Stricker, Y Beckham, MW Davidson, ML Gardel - PloS one, 2013 - journals.plos.org
… (b) Box plots of FA lengths in U2OS cells as a function of Y-27632 concentration (n = 101
(WT), 78 (1 µM), 134 (2 µM), 117 (5 µM), 124 (10 µM) FAs). (c) Representative GFP-actin …
(WT), 78 (1 µM), 134 (2 µM), 117 (5 µM), 124 (10 µM) FAs). (c) Representative GFP-actin …
[HTML][HTML] Arp2/3 inhibition induces amoeboid-like protrusions in MCF10A epithelial cells by reduced cytoskeletal-membrane coupling and focal adhesion assembly
Y Beckham, RJ Vasquez, J Stricker, K Sayegh… - PLoS …, 2014 - journals.plos.org
… The x, y positions of individual cells obtained by tracking in Metamorph and were … +(y t +τ
–y t ) 2 ]} and linear distance from starting point to end point {D = √[(x end –x start ) 2 +(y end –y …
–y t ) 2 ]} and linear distance from starting point to end point {D = √[(x end –x start ) 2 +(y end –y …
Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation
…, I Mambetsariev, Y Tian, Y Beckham… - American journal of …, 2015 - atsjournals.org
Reversible changes in lung microstructure accompany lung inflammation, although alterations
in tissue micromechanics and their impact on inflammation remain unknown. This study …
in tissue micromechanics and their impact on inflammation remain unknown. This study …
Development in frogs with large eggs and the origin of amniotes
RP Elinson, Y Beckham - Zoology, 2002 - Elsevier
The origin of the amniote egg is one of the most significant events in the evolution of
terrestrial vertebrates. This innovation was probably driven by increased egg size, and to find …
terrestrial vertebrates. This innovation was probably driven by increased egg size, and to find …
Dia1-dependent adhesions are required by epithelial tissues to initiate invasion
TB Fessenden, Y Beckham, M Perez-Neut… - Journal of Cell …, 2018 - rupress.org
… Image sequences were corrected for x/y drift using the Stackreg plugin in ImageJ and a
custom MATLAB script (MathWorks). Fluorescence imaging of cells expressing H2B-mCherry …
custom MATLAB script (MathWorks). Fluorescence imaging of cells expressing H2B-mCherry …
Localization of RNAs in oocytes of Eleutherodactylus coqui, a direct developing frog, differs from Xenopus laevis
YM Beckham, K Nath, RP Elinson - Evolution & development, 2003 - Wiley Online Library
Eleutherodactylus coqui develops directly on land to a frog. The large 3.5‐mm oocyte of E.
coqui has enough yolk to allow development without a feeding tadpole. In the smaller …
coqui has enough yolk to allow development without a feeding tadpole. In the smaller …