Lysosomes coordinate cellular metabolism and growth upon sensing of essential nutrients,
including cholesterol. Through bioinformatic analysis of lysosomal proteomes, we identified …

Overexpression and aggregation of α-synuclein (ASyn) are linked to the onset and pathology
of Parkinson's disease and related synucleinopathies. Elevated levels of the stress-…

Messenger RNA (mRNA) plays a critical role in cellular growth and development. However,
there have been limited methods available to visualize endogenous mRNA in living cells …

Labeling proteins with high specificity and efficiency is a fundamental prerequisite for
microscopic visualization of subcellular protein structures and interactions. Although the …

Accurate diagnostic testing is at the center of controlling infectious disease outbreaks. It allows
clinicians and public health practitioners to identify and treat infected individuals as well …

The centrosome serves as the main microtubule-organizing center in metazoan cells, yet
despite its functional importance, little is known mechanistically about the structure and …

Compressive sensing is a new field in signal processing and applied mathematics. It allows
one to simultaneously sample and compress signals which are known to have a sparse …

Ruthenium diimine complexes have previously been used to facilitate light-activated electron
transfer in the study of redox metalloproteins. Excitation at 488 nm leads to a photoexcited …

… , significantly improves 2-year invasive disease-free survival … a protocol-defined 5-year
follow-up sensitivity analysis and … At the 5-year follow-up, 1 year of extended adjuvant therapy …

… citron (Citrus medica var. sarcodactylis Swingle) were investigated. Two year old Fingered
citron plants … from ROS accumulation in Fingered citron leaves accompanied by increases in …