User profiles for W. Mallard

William Mallard

Cell Biologist, Harvard University
Verified email at g.harvard.edu
Cited by 18863

[HTML][HTML] Multiple knockout mouse models reveal lincRNAs are required for life and brain development

…, E Li, M Spence, SC Liapis, W Mallard… - elife, 2013 - elifesciences.org
10.7554/eLife.01749.001 Many studies are uncovering functional roles for long noncoding
RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in …

The NIST Chemistry WebBook: A chemical data resource on the internet

PJ Linstrom, WG Mallard - Journal of Chemical & Engineering …, 2001 - ACS Publications
The NIST Chemistry WebBook ( http://webbook.nist.gov ) is an Internet site that provides
access to chemical and physical property data both from NIST and other sources. The site was …

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells

…, C Galonska, R Pop, D Reyon, SQ Tsai, W Mallard… - Nature …, 2015 - nature.com
DNA methylation is a key epigenetic modification involved in regulating gene expression
and maintaining genomic integrity. Here we inactivated all three catalytically active DNA …

Soot inception in a methane/air diffusion flame as characterized by detailed species profiles

KC Smyth, JH Miller, RC Dorfman, WG Mallard… - Combustion and …, 1985 - Elsevier
Detailed species concentration profiles have been measured using optical and mass
spectrometric methods in an atmospheric pressure methane air diffusion flame burning on a …

Metabolite profiling of a NIST Standard Reference Material for human plasma (SRM 1950): GC-MS, LC-MS, NMR, and clinical laboratory analyses, libraries, and web …

…, KH Telu, PA Rudnick, WG Mallard… - Analytical …, 2013 - ACS Publications
Recent progress in metabolomics and the development of increasingly sensitive analytical
techniques have renewed interest in global profiling, ie, semiquantitative monitoring of all …

A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs

J Choi, S Lee, W Mallard, K Clement… - Nature …, 2015 - nature.com
The equivalence of human induced pluripotent stem cells (hiPSCs) and human embryonic
stem cells (hESCs) remains controversial. Here we use genetically matched hESC and hiPSC …

Deconvolution gas chromatography/mass spectrometry of urinary organic acids–potential for pattern recognition and automated identification of metabolic disorders

…, A Przyborowska, SE Stein, WG Mallard… - … in mass spectrometry, 1999 - Wiley Online Library
The National Institute of Standards and Technology (NIST) Automated Mass Spectral
Deconvolution and Identification System (AMDIS) is applied to a selection of data files obtained …

Development of a database of gas chromatographic retention properties of organic compounds

…, JJ Reed, IG Zenkevich, RL Brown, WG Mallard… - … of Chromatography A, 2007 - Elsevier
A comprehensive database of gas chromatographic retention properties of chemical
compounds has been developed using multiple literature sources. The National Institute of …

Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs

M Melé, K Mattioli, W Mallard, DM Shechner… - Genome …, 2017 - genome.cshlp.org
While long intergenic noncoding RNAs (lincRNAs) and mRNAs share similar biogenesis
pathways, these transcript classes differ in many regards. LincRNAs are less evolutionarily …

Dissecting neural differentiation regulatory networks through epigenetic footprinting

…, R Edri, Y Yaffe, J Donaghey, R Pop, W Mallard… - Nature, 2015 - nature.com
Abstract Models derived from human pluripotent stem cells that accurately recapitulate
neural development in vitro and allow for the generation of specific neuronal subtypes are of …