User profiles for W. Korff

Wyatt Korff

HHMI Janelia Research Campus
Verified email at janelia.hhmi.org
Cited by 3188

Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila

…, WJ Rowell, RM Johnston, TTB Ngo, N Chen, W Korff… - elife, 2014 - elifesciences.org
10.7554/eLife.04580.001 Animals discriminate stimuli, learn their predictive value and use
this knowledge to modify their behavior. In Drosophila, the mushroom body (MB) plays a key …

[HTML][HTML] Fast and sensitive GCaMP calcium indicators for imaging neural populations

…, R Zhang, MB Ahrens, GC Turner, SSH Wang, WL Korff… - Nature, 2023 - nature.com
… . To quantify P b for each fluorophore, their respective excitation rate (W) was obtained. The
excitation rate W for a laser source can be calculated as a product of extinction coefficient (ε (…

Whole-cell organelle segmentation in volume electron microscopy

…, J Clements, S Pang, CS Xu, J Funke, W Korff… - Nature, 2021 - nature.com
Cells contain hundreds of organelles and macromolecular assemblies. Obtaining a
complete understanding of their intricate organization requires the nanometre-level, three-…

Deadly strike mechanism of a mantis shrimp

SN Patek, WL Korff, RL Caldwell - Nature, 2004 - nature.com
Stomatopods (mantis shrimp) are well known for the feeding appendages they use to
smash shells and impale fish. Here we show that the peacock mantis shrimp (Odontodactylus …

[PDF][PDF] Reconstruction of 1,000 projection neurons reveals new cell types and organization of long-range connectivity in the mouse brain

…, JT Dudman, CR Gerfen, AW Hantman, W Korff… - Cell, 2019 - cell.com
Neuronal cell types are the nodes of neural circuits that determine the flow of information
within the brain. Neuronal morphology, especially the shape of the axonal arbor, provides an …

The functional organization of descending sensory-motor pathways in Drosophila

S Namiki, MH Dickinson, AM Wong, W Korff, GM Card - Elife, 2018 - elifesciences.org
10.7554/eLife.34272.001 In most animals, the brain controls the body via a set of descending
neurons (DNs) that traverse the neck. DN activity activates, maintains or modulates …

[PDF][PDF] Mapping the neural substrates of behavior

…, LA Umayam, A Lee, ML Phillips, GM Card, W Korff… - Cell, 2017 - cell.com
Assigning behavioral functions to neural structures has long been a central goal in
neuroscience and is a necessary first step toward a circuit-level understanding of how the brain …

A repeated molecular architecture across thalamic pathways

…, C Liu, V Valakh, L Wang, BC Shields, W Korff… - Nature …, 2019 - nature.com
The thalamus is the central communication hub of the forebrain and provides the cerebral
cortex with inputs from sensory organs, subcortical systems and the cortex itself. Multiple …

Optogenetic dissection of descending behavioral control in Drosophila

J Cande, S Namiki, J Qiu, W Korff, GM Card… - Elife, 2018 - elifesciences.org
10.7554/eLife.34275.001 In most animals, the brain makes behavioral decisions that are
transmitted by descending neurons to the nerve cord circuitry that produces behaviors. In …

Fast and sensitive GCaMP calcium indicators for imaging neural populations

…, R Zhang, MB Ahrens, GC Turner, SSH Wang, WL Korff… - Biorxiv, 2021 - biorxiv.org
Calcium imaging with protein-based indicators is widely used to follow neural activity in intact
nervous systems. The popular GCaMP indicators are based on the calcium-binding protein …