Cardiovascular disease is a major complication of diabetes mellitus, and improved strategies
for prevention and treatment are needed. Endothelial dysfunction contributes to the …

Spinal muscular atrophy (SMA) is a severe neuromuscular disorder due to a defect in the
survival motor neuron 1 (SMN1) gene. Its incidence is approximately 1 in 11,000 live births. In …

Astrocytes, through their close associations with synapses, can monitor and alter synaptic
function, thus actively controlling synaptic transmission in the adult brain. Besides their …

Background Trastuzumab emtansine is the current standard treatment for patients with
human epidermal growth factor receptor 2 (HER2)–positive metastatic breast cancer whose …

Reactive astrocytes are strongly induced by central nervous system (CNS) injury and disease,
but their role is poorly understood. Here we show that a subtype of reactive astrocytes, …

We present a new measurement of the inclusive and differential production cross sections
of J/ψ mesons and b hadrons in proton-antiproton collisions at s= 1960 G e V. The data …

We tested the hypothesis that de novo copy number variation (CNV) is associated with autism
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …

Importance The clinical management ofBRCA1andBRCA2mutation carriers requires accurate,
prospective cancer risk estimates. Objectives To estimate age-specific risks of breast, …

The generation of pluripotent stem cells from an individual patient would enable the large-scale
production of the cell types affected by that patient's disease. These cells could in turn be …

This paper proposes a framework for quantitatively evaluating interactive LLMs such as
ChatGPT using publicly available data sets. We carry out an extensive technical evaluation of …