Schizophrenic and bipolar disorders are similar in several epidemiologic respects, including
age at onset, lifetime risk, course of illness, worldwide distribution, risk for suicide, gender …

… Berrettini W , … Cunningham FG, Bangdiwala SI, Brown SS, Dean TM, Frederiksen M,
Rowland Hogue CJ, King T, Spencer Lukacz E, McCullough LB, Nicholson W, Petit NF …

Addictive disorders are partly heritable, chronic, relapsing conditions that account for a
tremendous disease burden. Currently available addiction pharmacotherapies are only …

Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …

Smoking is a leading global cause of disease and mortality 1 . We established the Oxford-GlaxoSmithKline
study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association …

Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

This study examined the association between two specific polymorphisms of the gene encoding
the μ-opioid receptor and treatment outcomes in alcohol-dependent patients who were …

Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable disorder,
but specific genetic factors underlying risk remain elusive. To assess the role of structural …

OBJECTIVE: The purpose of this study was to examine the role of perfectionism as a
phenotypic trait in anorexia nervosa and its relevance across clinical subtypes of this illness. …

Twin studies indicate that additive genetic effects explain most of the variance in nicotine
dependence (ND), a construct emphasizing habitual heavy smoking despite adverse …