User profiles for W. T. Ireland

William T Ireland

Postdoc at Harvard University
Verified email at seas.harvard.edu
Cited by 275

Systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria

NM Belliveau, SL Barnes, WT Ireland… - Proceedings of the …, 2018 - National Acad Sciences
Gene regulation is one of the most ubiquitous processes in biology. However, while the catalog
of bacterial genomes continues to expand rapidly, we remain ignorant about how almost …

[HTML][HTML] MAVE-NN: learning genotype-phenotype maps from multiplex assays of variant effect

A Tareen, M Kooshkbaghi, A Posfai, WT Ireland… - Genome biology, 2022 - Springer
… \(c_{n}^{\text {in}}\) and \(c_{n}^{\text {out}}\) respectively represent the number of reads
from the input and output samples (ie, pre-selection and post-selection libraries), and n→WT

Deciphering the regulatory genome of Escherichia coli, one hundred promoters at a time

WT Ireland, SM Beeler, E Flores-Bautista, NS McCarty… - Elife, 2020 - elifesciences.org
weight matrices. (A) CRP binds upstream of RNAP in the lacZYA promoter. Despite the
different measurement techniques for the two inferred position weight … position weight matrices …

[HTML][HTML] Mapping DNA sequence to transcription factor binding energy in vivo

SL Barnes, NM Belliveau, WT Ireland… - PLoS computational …, 2019 - journals.plos.org
… energy as Δε R = αε mat + Δε wt , where ε mat is the energy value obtained by summing the
matrix elements associated with a sequence, Δε wt is the binding energy associated with the …

[HTML][HTML] Evolution of DNA replication origin specification and gene silencing mechanisms

Y Hu, A Tareen, YJ Sheu, WT Ireland, C Speck… - Nature …, 2020 - nature.com
DNA replication in eukaryotic cells initiates from replication origins that bind the Origin
Recognition Complex (ORC). Origin establishment requires well-defined DNA sequence motifs in …

[HTML][HTML] Weight bias in educational settings: A systematic review

S Nutter, A Ireland, AS Alberga, I Brun, D Lefebvre… - Current obesity …, 2019 - Springer
… Although this review highlighted the impact of weight bias in educational settings, not all
aspects of weight bias or weight-related issues were captured. For example, this review did not …

[BOOK][B] Ireland, 1912-1985: politics and society

J Lee - 1989 - books.google.com
… perspective can illuminate the Irish scene, an understanding of Irish history may in turn
enrich wider historial perspectives. Yet the distinctive nature of the Irish case complicates the …

[BOOK][B] The natural history of Ireland

W Thompson - 1856 - books.google.com
In the will of the late William Thompson, Esq., of Belfast, the following paragraph occurs:—"
In the event of my decease before the publication of my work on the Natural History of Ireland

The relationship between low birth weight and socioeconomic status in Ireland

D Madden - Journal of biosocial science, 2014 - cambridge.org
… There is now fairly substantial evidence of a socioeconomic gradient in low birth weight for …
Growing Up in Ireland survey, this paper calculates this index for low birth weight arising from …

[HTML][HTML] Prevalence of overweight and obesity on the island of Ireland: results from the North South Survey of Children's Height, Weight and Body Mass Index, 2002

H Whelton, J Harrington, E Crowley, V Kelleher… - BMC public health, 2007 - Springer
… was to establish baseline data on the prevalence and correlates of overweight and obesity
among children and adolescents in the Republic of Ireland (RoI) and Northern Ireland (NI). …