User profiles for W. J. Tyler
William J. Tyler, Ph.D., "Jamie"Co-Founder IST, LLC; Prof BME @UAB Verified email at tylerlab.com Cited by 10124 |
From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning
WJ Tyler, M Alonso, CR Bramham… - Learning & …, 2002 - learnmem.cshlp.org
… 2001), it will be of paramount importance to establish if the activity-dependent release of
BDNF promotes the sculpting of dendritic spines in hippocampal pyramidal neurons (WJ Tyler …
BDNF promotes the sculpting of dendritic spines in hippocampal pyramidal neurons (WJ Tyler …
The mechanobiology of brain function
WJ Tyler - Nature Reviews Neuroscience, 2012 - nature.com
All cells are influenced by mechanical forces. In the brain, force-generating and load-bearing
proteins twist, turn, ratchet, flex, compress, expand and bend to mediate neuronal …
proteins twist, turn, ratchet, flex, compress, expand and bend to mediate neuronal …
Regulatory considerations for the clinical and research use of transcranial direct current stimulation (tDCS): review and recommendations from an expert panel
The field of transcranial electrical stimulation (tES) has experienced significant growth in the
past 15 years. One of the tES techniques leading this increased interest is transcranial direct …
past 15 years. One of the tES techniques leading this increased interest is transcranial direct …
[PDF][PDF] Transcranial pulsed ultrasound stimulates intact brain circuits
…, J Georges, A Yoshihiro, SIH Tillery, WJ Tyler - Neuron, 2010 - cell.com
Electromagnetic-based methods of stimulating brain activity require invasive procedures or
have other limitations. Deep-brain stimulation requires surgically implanted electrodes. …
have other limitations. Deep-brain stimulation requires surgically implanted electrodes. …
Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans
…, J Mueller, A Barbour, A Williams, WJ Tyler - Nature …, 2014 - nature.com
Improved methods of noninvasively modulating human brain function are needed. Here we
probed the influence of transcranial focused ultrasound (tFUS) targeted to the human …
probed the influence of transcranial focused ultrasound (tFUS) targeted to the human …
[HTML][HTML] Remote excitation of neuronal circuits using low-intensity, low-frequency ultrasound
Possessing the ability to noninvasively elicit brain circuit activity yields immense experimental
and therapeutic power. Most currently employed neurostimulation methods rely on the …
and therapeutic power. Most currently employed neurostimulation methods rely on the …
BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses
WJ Tyler, LD Pozzo-Miller - Journal of Neuroscience, 2001 - Soc Neuroscience
Brain-derived neurotrophic factor (BDNF) is emerging as a key mediator of activity-dependent
modifications of synaptic strength in the CNS. We investigated the hypothesis that BDNF …
modifications of synaptic strength in the CNS. We investigated the hypothesis that BDNF …
Ultrasonic neuromodulation by brain stimulation with transcranial ultrasound
Brain stimulation methods are indispensable to the study of brain function. They have also
proven effective for treating some neurological disorders. Historically used for medical imaging…
proven effective for treating some neurological disorders. Historically used for medical imaging…
Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones
WJ Tyler, L Pozzo‐Miller - The Journal of physiology, 2003 - Wiley Online Library
The refinement and plasticity of neuronal connections require synaptic activity and neurotrophin
signalling; their specific contributions and interplay are, however, poorly understood. We …
signalling; their specific contributions and interplay are, however, poorly understood. We …
Noninvasive neuromodulation with ultrasound? A continuum mechanics hypothesis
WJ Tyler - The Neuroscientist, 2011 - journals.sagepub.com
Deep brain stimulation and vagal nerve stimulation are therapeutically effective in treating
some neurological diseases and psychiatric disorders. Optogenetic-based neurostimulation …
some neurological diseases and psychiatric disorders. Optogenetic-based neurostimulation …