Triple-negative breast cancer, so called because it lacks expression of the estrogen receptor,
progesterone receptor, and HER2, is often, but not always, a basal-like breast cancer. This …

The discovery of the first gene associated with hereditary breast cancer, BRCA1, was
anticipated to greatly increase our understanding of both hereditary and sporadic forms of breast …

… Foulkes, MB, Ph.D., Department of Medical Genetics, Room A801, Sir Mortimer B. Davis …
Foulkes WD. A tale of four syndromes: Familial adenomatous polyposis, Gardner syndrome, …

The vast majority of coding variants are rare, and assessment of the contribution of rare
variants to complex traits is hampered by low statistical power and limited functional data. …

… WD Foulkes is a Senior Chercheur Clinicien Boursier of the FRSQ. … Chappuis PO, Rosenblatt
J, Foulkes WD. The influence of familial and hereditary factors on the prognosis of breast …

Background Immunohistochemical markers are often used to classify breast cancer into
subtypes that are biologically distinct and behave differently. The aim of this study was to …

Background Germline loss-of-function mutations in PALB2 are known to confer a predisposition
to breast cancer. However, the lifetime risk of breast cancer that is conferred by such …

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Genetic testing of cancer susceptibility genes is now widely applied in clinical practice to
predict risk of developing cancer. In general, sequence‐based testing of germline DNA is used …

8 Ss (paid volunteer males, ages 17-27) were placed in the information-gathering sleep
situation for 57 (nonconsecutive) nights. Ss were awakened during various stages of sleep (…