Oral Administration and Selective Uptake of Polymeric Nanoparticles in Drosophila Larvae as an in Vivo Model

S Jiang, CP Teng, WC Puah, M Wasser… - ACS Biomaterials …, 2015 - ACS Publications
In this article, Drosophila larvae are applied as an in vivo model to investigate the transport
and uptake of polymeric nanoparticles in the larval digestive tract after oral administration. …

[HTML][HTML] Live imaging of muscle histolysis in Drosophila metamorphosis

Y Kuleesha, WC Puah, M Wasser - BMC Developmental Biology, 2016 - Springer
Background The contribution of programmed cell death (PCD) to muscle wasting disorders
remains a matter of debate. Drosophila melanogaster metamorphosis offers the opportunity …

A model of muscle atrophy based on live microscopy of muscle remodelling in Drosophila metamorphosis

Y Kuleesha, WC Puah… - Royal Society open …, 2016 - royalsocietypublishing.org
Genes controlling muscle size and survival play important roles in muscle wasting diseases.
In Drosophila melanogaster metamorphosis, larval abdominal muscles undergo two …

[HTML][HTML] Cell cycle phase classification in 3D in vivo microscopy of Drosophila embryogenesis

TH Du, WC Puah, M Wasser - BMC bioinformatics, 2011 - Springer
Background Cell divisions play critical roles in disease and development. The analysis of
cell division phenotypes in high content image-based screening and time-lapse microscopy …

[HTML][HTML] Live imaging of muscles in Drosophila metamorphosis: Towards high-throughput gene identification and function analysis

WC Puah, M Wasser - Methods, 2016 - Elsevier
Time-lapse microscopy in developmental biology is an emerging tool for functional genomics.
Phenotypic effects of gene perturbations can be studied non-invasively at multiple time …

[HTML][HTML] FMAj: a tool for high content analysis of muscle dynamics in Drosophila metamorphosis

Y Kuleesha, WC Puah, F Lin, M Wasser - BMC bioinformatics, 2014 - Springer
WC was involved in laboratory experiments and microscopy. LF provided academic
advice on K's research work in image processing and algorithm design. MW conceived and …

Quantitative microscopy uncovers ploidy changes during mitosis in live Drosophila embryos and their effect on nuclear size

WC Puah, R Chinta, M Wasser - Biology open, 2017 - journals.biologists.com
… Wee Choo Puah … Wee Choo Puah … (A) A batch file converter (TLM-converter) fragments
large multi-dimensional datasets for easier downstream processing into smaller portions (Puah et …

TLM-Converter: reorganization of long time-lapse microscopy datasets for downstream image analysis

WC Puah, LP Cheok, M Biro, WT Ng, M Wasser - BioTechniques, 2011 - Taylor & Francis
Automated microscopy enables in vivo studies in developmental biology over long periods
of time. Time-lapse recordings in three or more dimensions to study the dynamics of …

[HTML][HTML] Phenotypic and Genetic Diversity of Aeromonas Species Isolated from Fresh Water Lakes in Malaysia

WC Khor, SM Puah, JAMA Tan, SD Puthucheary… - PLoS …, 2015 - journals.plos.org
Gram-negative bacilli of the genus Aeromonas are primarily inhabitants of the aquatic
environment. Humans acquire this organism from a wide range of food and water sources as well …

FMAj: a tool for high content analysis of muscle dynamics in Drosophila metamorphosis

WC Puah, Y Kuleesha, F Lin, M Wasser - 2015 - dr.ntu.edu.sg
WC was involved in laboratory experiments and microscopy. LF provided academic
advice on KLs research work in image processing and algorithm design. MW conceived and …