At the time of this writing, searching Google Scholar for ‘light-sheet microscopy’ returns
almost 8500 results; over three-quarters of which were published in the last 5 years alone. …

Pushing the frontier of fluorescence microscopy requires the design of enhanced
fluorophores with finely tuned properties. We recently discovered that incorporation of four-membered …

Coupling of autonomous cellular oscillators is an essential aspect of circadian clock
function but little is known about its circuit requirements. Functional ablation of the pigment-…

Imaging fast cellular dynamics across large specimens requires high resolution in all dimensions,
high imaging speeds, good physical coverage and low photo-damage. To meet these …

Optimal image quality in light-sheet microscopy requires a perfect overlap between the
illuminating light sheet and the focal plane of the detection objective. However, mismatches …

Understanding how the brain works in tight concert with the rest of the central nervous system
(CNS) hinges upon knowledge of coordinated activity patterns across the whole CNS. We …

We present the Real-time Accurate Cell-shape Extractor (RACE), a high-throughput image
analysis framework for automated three-dimensional cell segmentation in large-scale images…

A subset of Drosophila neurons that expresses crustacean cardioactive peptide (CCAP) has
been shown previously to make the hormone bursicon, which is required for cuticle tanning …

OPTIMAL foraging theory is based on the assumption that natural selection favours animals
that forage most efficiently 1–3 . But such selection does not act directly on foraging efficiency…

Light-sheet microscopy is a powerful method for imaging the development and function of
complex biological systems at high spatiotemporal resolution and over long time scales. Such …