Calcium is a key signaling ion involved in many different intracellular and extracellular
processes ranging from synaptic activity to cell-cell communication and adhesion. The exact …

Several epidemiological studies indicate that moderate consumption of red wine is associated
with a lower incidence of dementia and Alzheimer's disease. Red wine is enriched in …

Since the discovery of prion diseases, the concept has emerged that a protein could be a
transmissible pathogen. As such, this transmissible pathogen agent can transfer its …

Alzheimer disease is an age-related neurodegenerative disorder characterized by amyloid-β
(Aβ) peptide deposition into cerebral amyloid plaques. The natural polyphenol resveratrol …

Alzheimer's disease (AD) is characterized by a substantial degeneration of pyramidal neurons
and the appearance of neuritic plaques and neurofibrillary tangles. Here we present a …

… Valérie Vingtdeux… Valérie Vingtdeux… that resveratrol is both bioavailable and bioactive
in the brain after oral dosing (Vingtdeux et al. 2010). We followed the same protocol to evaluate …

Recognition of sweet, bitter and umami tastes requires the non-vesicular release from taste
bud cells of ATP, which acts as a neurotransmitter to activate afferent neural gustatory …

Alzheimer's disease (AD) is a genetically heterogeneous disorder characterized by early
hippocampal atrophy and cerebral amyloid-β (Aβ) peptide deposition. Using TissueInfo to …

Tauopathies represent a class of neurodegenerative disorders characterized by abnormal
tau phosphorylation and aggregation into neuronal paired helical filaments (PHFs) and …

AMP-activated protein kinase (AMPK) is a metabolic sensor involved in intracellular energy
metabolism through the control of several homeostatic mechanisms, which include …