Steroid-resistant nephrotic syndrome (SRNS) is the second most frequent cause of ESRD in
the first two decades of life. Effective treatment is lacking. First insights into disease …

Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of end-stage renal failure.
Identification of single-gene causes of SRNS has generated some insights into its …

Identification of single-gene causes of steroid-resistant nephrotic syndrome (SRNS) has
furthered the understanding of the pathogenesis of this disease. Here, using a combination of …

<p id="p001">Integrin α₃ is a transmembrane integrin receptor subunit that
mediates signals between the cells and their microenvironment. We identified three patients …

Nephrotic syndrome (NS) is divided into steroid-sensitive (SSNS) and -resistant (SRNS)
variants. SRNS causes end-stage kidney disease, which cannot be cured. While the disease …

Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of progressive renal function
decline and affects millions of people. In a recent study, 30% of SRNS cases evaluated …

The identification of recessive disease-causing genes by homozygosity mapping is often
restricted by lack of suitable consanguineous families. To overcome these limitations, we apply …

Background The DiGeorge syndrome, the most common of the microdeletion syndromes,
affects multiple organs, including the heart, the nervous system, and the kidney. It is caused by …

Nephrotic syndrome (NS) is a genetically heterogeneous group of diseases that are divided
into steroid-sensitive NS (SSNS) and steroid-resistant NS (SRNS). SRNS inevitably leads to …

Nephrotic syndrome (NS), the association of gross proteinuria, hypoalbuminaemia, edema,
and hyperlipidemia, can be clinically divided into steroid-sensitive (SSNS) and steroid-…