User profiles for V. Stathias

Vasileios Stathias

University of Miami
Verified email at med.miami.edu
Cited by 2413

[PDF][PDF] The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations

…, A Lachmann, MV Kuleshov, A Ma'ayan, V Stathias… - Cell systems, 2018 - cell.com
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common
Fund program that catalogs how human cells globally respond to chemical, genetic, and …

[PDF][PDF] Proteogenomic data and resources for pan-cancer analysis

…, SA Carr, T Liu, T Hiltke, TM Yaron, V Stathias… - Cancer cell, 2023 - cell.com
The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC)
investigates tumors from a proteogenomic perspective, creating rich multi-omics datasets …

Machine and deep learning approaches for cancer drug repurposing

NT Issa, V Stathias, S Schürer… - Seminars in cancer …, 2021 - Elsevier
Abstract Knowledge of the underpinnings of cancer initiation, progression and metastasis has
increased exponentially in recent years. Advanced “omics” coupled with machine learning …

[PDF][PDF] A proteogenomic portrait of lung squamous cell carcinoma

…, T Omelchenko, Y Geffen, EJ Bergstrom, V Stathias… - Cell, 2021 - cell.com
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …

[PDF][PDF] Proteogenomic and metabolomic characterization of human glioblastoma

…, A Colaprico, JH Rothstein, R Hong, V Stathias… - Cancer cell, 2021 - cell.com
Glioblastoma (GBM) is the most aggressive nervous system cancer. Understanding its
molecular pathogenesis is crucial to improving diagnosis and treatment. Integrated analysis of …

[PDF][PDF] Integrated proteogenomic characterization across major histological types of pediatric brain cancer

…, A Calinawan, JR Whiteaker, A Colaprico, V Stathias… - Cell, 2020 - cell.com
We report a comprehensive proteogenomics analysis, including whole-genome sequencing,
RNA sequencing, and proteomics and phosphoproteomics profiling, of 218 tumors across 7 …

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response …

A Koleti, R Terryn, V Stathias, C Chung… - Nucleic acids …, 2018 - academic.oup.com
The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national
consortium funded by the NIH to generate a diverse and extensive reference library of cell-…

[HTML][HTML] Connecting omics signatures and revealing biological mechanisms with iLINCS

…, JF Reichard, K Roberts, V Stathias… - Nature …, 2022 - nature.com
There are only a few platforms that integrate multiple omics data types, bioinformatics tools,
and interfaces for integrative analyses and visualization that do not require programming …

[PDF][PDF] Pan-cancer proteogenomics connects oncogenic drivers to functional states

…, C Tokheim, MH Bailey, TM Yaron, V Stathias… - Cell, 2023 - cell.com
Cancer driver events refer to key genetic aberrations that drive oncogenesis; however, their
exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan-…

LINCS Data Portal 2.0: next generation access point for perturbation-response signatures

V Stathias, J Turner, A Koleti, D Vidovic… - Nucleic acids …, 2020 - academic.oup.com
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common
Fund program with the goal of generating a large-scale and comprehensive catalogue of …