User profiles for V. Pelechano

Vicent Pelechano

- Verified email at ki.se - Cited by 6500

Vicente Pelechano

- Verified email at dsic.upv.es - Cited by 4934

Gene regulation by antisense transcription

V Pelechano, LM Steinmetz - Nature Reviews Genetics, 2013 - nature.com
Antisense transcription, which was initially considered by many as transcriptional noise, is
increasingly being recognized as an important regulator of gene expression. It is widespread …

Functional consequences of bidirectional promoters

W Wei, V Pelechano, AI Järvelin, LM Steinmetz - Trends in Genetics, 2011 - cell.com
Several studies have shown that promoters of protein-coding genes are origins of pervasive
non-coding RNA transcription and can initiate transcription in both directions. However, only …

VIVACE: A framework for the systematic evaluation of variability support in process-aware information systems

…, V Torres, B Weber, M Reichert, V Pelechano - Information and Software …, 2015 - Elsevier
Context The increasing adoption of process-aware information systems (PAISs) such as
workflow management systems, enterprise resource planning systems, or case management …

A global genetic interaction network maps a wiring diagram of cellular function

…, W Wang, M Usaj, J Hanchard, SD Lee, V Pelechano… - Science, 2016 - science.org
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …

[PDF][PDF] Controlling individual agents in high-density crowd simulation

N Pelechano, JM Allbeck, NI Badler - Symposium on Computer …, 2007 - researchgate.net
Simulating the motion of realistic, large, dense crowds of autonomous agents is still a
challenge for the computer graphics community. Typical approaches either resemble particle …

Rapid detection of COVID-19 coronavirus using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform

…, S Wu, X Hao, X Dong, L Mao, V Pelechano… - Clinical …, 2020 - academic.oup.com
In summary, we have developed a RT-LAMP-based method, optimized for the detection of
SARS-CoV-2. Our method is robust, accurate, and simple to use. We hope that this method …

Extensive transcriptional heterogeneity revealed by isoform profiling

V Pelechano, W Wei, LM Steinmetz - Nature, 2013 - nature.com
Transcript function is determined by sequence elements arranged on an individual RNA
molecule. Variation in transcripts can affect messenger RNA stability, localization and …

Evacuation simulation models: Challenges in modeling high rise building evacuation with cellular automata approaches

N Pelechano, A Malkawi - Automation in construction, 2008 - Elsevier
Building evacuation simulation provides designers with an efficient way of testing the safety
of a building before construction. A significant number of models have been developed in a …

Modeling crowd and trained leader behavior during building evacuation

N Pelechano, NI Badler - IEEE computer graphics and …, 2006 - ieeexplore.ieee.org
This article considers animating evacuation in complex buildings by crowds who might not
know the structure's connectivity, or who find routes accidentally blocked. It takes into account …

[PDF][PDF] Widespread co-translational RNA decay reveals ribosome dynamics

V Pelechano, W Wei, LM Steinmetz - Cell, 2015 - cell.com
It is generally assumed that mRNAs undergoing translation are protected from decay. Here,
we show that mRNAs are, in fact, co-translationally degraded. This is a widespread and …