Gene regulation by antisense transcription
V Pelechano, LM Steinmetz - Nature Reviews Genetics, 2013 - nature.com
Antisense transcription, which was initially considered by many as transcriptional noise, is
increasingly being recognized as an important regulator of gene expression. It is widespread …
increasingly being recognized as an important regulator of gene expression. It is widespread …
Functional consequences of bidirectional promoters
Several studies have shown that promoters of protein-coding genes are origins of pervasive
non-coding RNA transcription and can initiate transcription in both directions. However, only …
non-coding RNA transcription and can initiate transcription in both directions. However, only …
VIVACE: A framework for the systematic evaluation of variability support in process-aware information systems
Context The increasing adoption of process-aware information systems (PAISs) such as
workflow management systems, enterprise resource planning systems, or case management …
workflow management systems, enterprise resource planning systems, or case management …
A global genetic interaction network maps a wiring diagram of cellular function
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …
[PDF][PDF] Controlling individual agents in high-density crowd simulation
Simulating the motion of realistic, large, dense crowds of autonomous agents is still a
challenge for the computer graphics community. Typical approaches either resemble particle …
challenge for the computer graphics community. Typical approaches either resemble particle …
Rapid detection of COVID-19 coronavirus using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform
…, S Wu, X Hao, X Dong, L Mao, V Pelechano… - Clinical …, 2020 - academic.oup.com
In summary, we have developed a RT-LAMP-based method, optimized for the detection of
SARS-CoV-2. Our method is robust, accurate, and simple to use. We hope that this method …
SARS-CoV-2. Our method is robust, accurate, and simple to use. We hope that this method …
Extensive transcriptional heterogeneity revealed by isoform profiling
Transcript function is determined by sequence elements arranged on an individual RNA
molecule. Variation in transcripts can affect messenger RNA stability, localization and …
molecule. Variation in transcripts can affect messenger RNA stability, localization and …
Evacuation simulation models: Challenges in modeling high rise building evacuation with cellular automata approaches
N Pelechano, A Malkawi - Automation in construction, 2008 - Elsevier
Building evacuation simulation provides designers with an efficient way of testing the safety
of a building before construction. A significant number of models have been developed in a …
of a building before construction. A significant number of models have been developed in a …
Modeling crowd and trained leader behavior during building evacuation
N Pelechano, NI Badler - IEEE computer graphics and …, 2006 - ieeexplore.ieee.org
This article considers animating evacuation in complex buildings by crowds who might not
know the structure's connectivity, or who find routes accidentally blocked. It takes into account …
know the structure's connectivity, or who find routes accidentally blocked. It takes into account …
[PDF][PDF] Widespread co-translational RNA decay reveals ribosome dynamics
It is generally assumed that mRNAs undergoing translation are protected from decay. Here,
we show that mRNAs are, in fact, co-translationally degraded. This is a widespread and …
we show that mRNAs are, in fact, co-translationally degraded. This is a widespread and …