X-linked adrenoleukodystrophy (ALD) is a severe brain demyelinating disease in boys that
is caused by a deficiency in ALD protein, an adenosine triphosphate–binding cassette …

Importance Extenuating circumstances can trigger unplanned changes to randomized trials
and introduce methodological, ethical, feasibility, and analytical challenges that can …

… Veronique Kiermer … Veronique Kiermer … Rusk, N., Kiermer, V. Primer: Sequencing—the
next generation. Nat Methods 5, 15 (2008). …

In keeping with the growing movement in scientific publishing toward transparency in data
and methods, we propose changes to journal authorship policies and procedures to provide …

We report that HDAC7, a class II histone deacetylase, is highly expressed in CD4 + CD8 +
double-positive thymocytes. HDAC7 inhibits the expression of Nur77, an orphan receptor …

Although the Journal Impact Factor (JIF) is widely acknowledged to be a poor indicator of the
quality of individual papers, it is used routinely to evaluate research and researchers. Here, …

The human immunodeficiency virus (HIV) Tat protein plays an essential role in promoting
efficient transcriptional elongation of viral transcripts. We report that the transcriptional co‐…

The HIV transcriptional activator Tat is acetylated by p300 at a single lysine residue in the
TAR RNA binding domain. We have generated monoclonal and polyclonal antibodies specific …

Transparency in reporting benefits scientific communication on many levels. While specific
needs and expectations vary across fields, the effective interpretation and use of research …

Lentiviral vectors have demonstrated great potential as gene therapy vectors mediating
efficient ex vivo and in vivo gene delivery and long-term transgene expression in both dividing …