We discuss the development of predictive choice models that go beyond the random utility
model in its narrowest formulation. Such approaches incorporate several elements of …

Chondrocytes are responsible for the maintenance of the articular cartilage. A loss of
homeostasis in cartilage contributes to the development of osteoarthritis (OA) when the synthetic …

Hair is a very important and distinctive feature that plays a major role in self perception. To
some extent, it expresses our personality and who we are. Hair is one of the few physical …

Background Viruses are a significant player in many biosphere and human ecosystems, but
most signals remain “hidden” in metagenomic/metatranscriptomic sequence datasets due to …

Microbial and viral communities transform the chemistry of Earth's ecosystems, yet the specific
reactions catalyzed by these biological engines are hard to decode due to the absence of …

• Behavioral inhibition is a laboratory-based temperamental category by the tendency to
constrict behavior in unfamiliar situations and assumed to reflect low thresholds of limbic arousal…

Background Studies that have evaluated the use of intravenous vitamin C in adults with
sepsis who were receiving vasopressor therapy in the intensive care unit (ICU) have shown …

Exome and whole-genome sequencing are becoming increasingly routine approaches in
Mendelian disease diagnosis. Despite their success, the current diagnostic rate for genomic …

“Behavioral inhibition to the unfamiliar‘’ is a temperamental construct reflecting the tendency
to be shy, timid, and constrained in novel situations. Previous work has suggested that it …

Background The interleukin‐17 cytokine family plays a central role in psoriasis
pathogenesis. Objectives To evaluate the efficacy and safety of brodalumab, a human anti‐interleukin‐17 …