User profiles for V. K. Kozyreva

Varvara Kozyreva

California Department of Public Health
Verified email at cdph.ca.gov
Cited by 544

Validation and implementation of clinical laboratory improvements act-compliant whole-genome sequencing in the public health microbiology laboratory

VK Kozyreva, CL Truong, AL Greninger… - Journal of clinical …, 2017 - Am Soc Microbiol
Public health microbiology laboratories (PHLs) are on the cusp of unprecedented improvements
in pathogen identification, antibiotic resistance detection, and outbreak investigation by …

Recent outbreaks of shigellosis in California caused by two distinct populations of Shigella sonnei with either increased virulence or fluoroquinolone resistance

VK Kozyreva, G Jospin, AL Greninger, JP Watt… - Msphere, 2016 - Am Soc Microbiol
Shigella sonnei has caused unusually large outbreaks of shigellosis in California in 2014 and
2015. Preliminary data indicated the involvement of two distinct bacterial populations, one …

Dual targeting of mesenchymal and amoeboid motility hinders metastatic behavior

…, YV Loskutov, KM Marinak, VK Kozyreva… - Molecular Cancer …, 2017 - AACR
Commonly upregulated in human cancers, the scaffolding protein NEDD9/HEF1 is a known
regulator of mesenchymal migration and cancer cell plasticity. However, the functional role …

NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast …

YV Loskutov, PY Kozyulina, VK Kozyreva, RJ Ice… - Oncogene, 2015 - nature.com
NEDD9 is an established marker of invasive and metastatic cancers. NEDD9 downregulation
has been shown to dramatically reduce cell invasion and metastasis in multiple tumors. …

NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6–dependent manner

VK Kozyreva, SL McLaughlin, RH Livengood… - Molecular Cancer …, 2014 - AACR
The prometastatic protein NEDD9 (neural precursor cell expressed, developmentally
downregulated 9) is highly expressed in many cancers and is required for mesenchymal individual …

[HTML][HTML] Laboratory Investigation of Salmonella enterica serovar Poona Outbreak in California: Comparison of Pulsed-Field Gel Electrophoresis (PFGE) and Whole …

VK Kozyreva, J Crandall, A Sabol, A Poe, P Zhang… - PLoS …, 2016 - ncbi.nlm.nih.gov
Methods: CA Salmonella Poona isolates, collected from July to August 2015, were genotyped
by PFGE using XbaI restriction enzyme. WGS was done using Nextera XT library kit with …

Combination of eribulin and Aurora A inhibitor MLN8237 prevents metastatic colonization and induces cytotoxic autophagy in breast cancer

VK Kozyreva, AA Kiseleva, RJ Ice, BC Jones… - Molecular cancer …, 2016 - AACR
VK Kozyreva and AA Kiseleva contributed equally to this article. … Writing, review, and/or
revision of the manuscript: VK Kozyreva, RJ Ice, K. Marinak, RH Livengood, MA Salkeni, S. Wen, …

NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis

…, PY Kozyulina, RH Livengood, VK Kozyreva… - Molecular Cancer …, 2014 - AACR
The scaffolding protein NEDD9 is an established prometastatic marker in several cancers.
Nevertheless, the molecular mechanisms of NEDD9-driven metastasis in cancers remain ill-…

Bacterial Resistance Studies Using In Vitro Dynamic Models: the Predictive Power of the Mutant Prevention and Minimum Inhibitory Antibiotic Concentrations

…, DS Shlykova, YA Portnoy, VK Kozyreva… - Antimicrobial agents …, 2013 - Am Soc Microbiol
In light of the concept of the mutant selection window, ie, the range between the MIC and the
mutant prevention concentration (MPC), MPC-related pharmacokinetic indices should be …

[HTML][HTML] First detection of VIM-4 metallo-β-lactamase-producing Escherichia coli in Russia

…, DY Mudrak, EY Skleenova, VK Kozyreva… - Clinical Microbiology …, 2012 - Elsevier
An Escherichia coli isolate co-producing VIM-4 metallo-β-lactamase and CTX-M-15 extended
spectrum β-lactamase was recovered from the urine of a patient with head trauma in …