Firm attachments between kinetochores and dynamic spindle microtubules (MTs) are important
for accurate chromosome segregation. Centromere protein F (CENP-F) has been shown …

Dynamic microtubule ends exert pulling and pushing forces on intracellular membranes and
organelles. However, the mechanical linkage of microtubule tips to their cargoes is poorly …

One of the simplest molecular motors, a biological microtubule, is reviewed as an example of
a highly nonequilibrium molecular machine capable of stochastic transitions between slow …

Detection methods based on rolling circle amplification (RCA) have been applied to a large
number of targets in molecular biology. The key feature of RCA-based methods as well as …

Comparative bioinformatic analysis is the cornerstone of the study of enzymes’ structure-function
relationship. However, numerous enzymes that derive from a common ancestor and …

Comparative bioinformatics is the cornerstone of computational approaches to
understanding structure-functional relationship in enzymes. The members of α/β hydrolase-fold …

Aim. To develop an information basis for the formation and implementation of multimedia
models for the diagnosis and treatment of depersonalized cases of cardiovascular diseases (…

Aim. To create a methodological base for distance learning of cardiology healthcare
professionals—multimedia clinical diagnostic tasks. Material and methods. The interdisciplinary …

During evolution of proteins from a common ancestor, one functional property can be
preserved while others can vary leading to functional diversity. A systematic study of the …

Superfamily of alpha-beta hydrolases is one of the largest groups of structurally related
enzymes with diverse catalytic functions. Bioinformatic analysis was used to study how lipase …