User profiles for U. Osby

Urban Ösby

MD, Karolinska Institutet
Verified email at ki.se
Cited by 11306

Genome-wide association study identifies 30 loci associated with bipolar disorder

…, ML Hamshere, M Hautzinger, U Heilbronner… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …

Excess mortality in bipolar and unipolar disorder in Sweden

U Ösby, L Brandt, N Correia, A Ekbom… - Archives of general …, 2001 - jamanetwork.com
Background Selected groups of patients with bipolar and unipolar disorder have an increased
mortality rate from suicide and natural causes of death. However, there has been no …

Mortality and causes of death in schizophrenia in Stockholm county, Sweden

U Ösby, N Correia, L Brandt, A Ekbom, P Sparén - Schizophrenia research, 2000 - Elsevier
A study of mortality for all patients with a first hospital diagnosis of schizophrenia in Stockholm
County, Sweden, during 1973 to 1995 was performed, by linking the in-patient register …

[HTML][HTML] Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden

…, K Wahlbeck, J Hällgren, J Westman, U Ösby… - PloS one, 2013 - journals.plos.org
Background Excess mortality among patients with severe mental disorders has not
previously been investigated in detail in large complete national populations. Objective To …

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

L Hou, U Heilbronner, F Degenhardt, M Adli… - The Lancet, 2016 - thelancet.com
Background Lithium is a first-line treatment in bipolar disorder, but individual response is
variable. Previous studies have suggested that lithium response is a heritable trait. However, …

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder

…, RE Handsaker, L Backlund, U Ösby… - Molecular …, 2012 - nature.com
Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable psychiatric disorders
with overlapping susceptibility loci and symptomatology. We conducted a genome-wide …

[HTML][HTML] Life expectancy and death by diseases of the circulatory system in patients with bipolar disorder or schizophrenia in the Nordic countries

…, K Wahlbeck, J Hällgren, J Westman, U Ösby… - PloS one, 2013 - journals.plos.org
Objective Excess mortality from diseases and medical conditions (natural death) in persons
with psychiatric disorders has been extensively reported. Even in the Nordic countries with …

Time trends in schizophrenia mortality in Stockholm county, Sweden: cohort study

U Ösby, N Correia, L Brandt, A Ekbom, P Sparén - Bmj, 2000 - bmj.com
Although mortality in patients with schizophrenia is two to three times higher than that in the
general population, little is known about time trends in mortality rates. 1-3 We aimed to …

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

…, J Hauser, U Heilbronner… - Human molecular …, 2016 - academic.oup.com
Bipolar disorder (BD) is a genetically complex mental illness characterized by severe
oscillations of mood and behaviour. Genome-wide association studies (GWAS) have identified …

Evaluation of diagnostic procedures in Swedish patients with schizophrenia and related psychoses

…, A Ekholm, R Adolfsson, M Vares, U Ösby… - Nordic journal of …, 2005 - Taylor & Francis
We aimed to estimate the value of structured interviews, medical records and Swedish
register diagnoses for assessing lifetime diagnosis of patients with schizophrenia. Psychiatric …