RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …

… Matthias W Hentze and Thomas Preiss … Castelló A, Fischer B, Eichelbaum K, Horos R,
Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J …

… Preiss T. The end in sight:poly(A), translation and mRNA stability in eukaryotes. In:
Brakier-… Preiss T, Hentze MW. Dual function of the messenger RNA cap structure in poly(A)-tail-…

RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two
complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a …

… a C to T sequence … to T conversion patterns ( Figure 1 C and D show results for 2 mm data;
see also Table 1 and Supplementary Table S4 ). R-Luc RNA showed almost complete C to T …

MicroRNAs (miRNAs) repress translation of target mRNAs by interaction with partially
mismatched sequences in their 3′ UTR. The mechanism by which they act on translation has …

The messenger RNA 3′ poly(A) tail critically affects the initiation and control of translation
in eukaryotes 1 , 2 , 3 . By analogy to elements involved in transcription initiation, the poly(A) …

… and thereby restrict antigen presentation to cytotoxic T cells through the MHC class I pathway
… translation and restricted endogenous presentation of CD8 + T-cell epitopes 6 . This purine …

In the past century, few areas of biology advanced as much as our understanding of the
pathways of intermediary metabolism. Initially considered unimportant in terms of gene …

RNA-binding proteins (RBPs) control all aspects of RNA fate, and defects in their function
underlie a broad spectrum of human pathologies. We focus here on two recent studies that …