… diverse effects on T cell subtypes: Calcitriol suppresses T helper (Th) cell proliferation,
differentiation and modulates their cytokine production [77]. In particular, treatment of T cells with …

Background Despite indications from epidemiological trials that higher blood glucose
concentrations are associated with a higher risk for developing micro‐and macrovascular …

… Horvath and TR Pieber performed clinical trials with short and long-acting insulin analogues
and insulin pumps for Aventis, Eli Lilly, Novo Nordisk and Roche. TR Pieber was or is a …

… Based on a model, the output trajectory y(t + k|t), k = 1,...,N, is estimated for any given control
sequence u(t +k|t) over a prediction horizon N. The model primary use is to determine the …

Aging is associated with an increased risk of cardiovascular disease and death. Here we
show that oral supplementation of the natural polyamine spermidine extends the lifespan of …

… with the respective baseline responses by paired Student t test or Wilcoxon signed rank
test … Group differences were tested by unpaired Student t test or Mann-Whitney U test. A two-…

Background Degludec is an ultralong-acting, once-daily basal insulin that is approved for
use in adults, adolescents, and children with diabetes. Previous open-label studies have …

Acetyl-coenzyme A (AcCoA) is a major integrator of the nutritional status at the crossroads
of fat, sugar, and protein catabolism. Here we show that nutrient starvation causes rapid …

… Pieber). Department of internal Medicine, Division of Nephrology, University of Heidelberg,
… & Lim, T. Plasma 25‑hydroxyvitamin D3 and its relation to physical activity and other heart …

… For secondary end points, we used a t test or the Mann-Whitney test for continuous
variables and the χ 2 or Fisher exact test for categorical variables. Laboratory parameters were …