Transcription of endothelial‐leukocyte adhesion molecule‐1 (E‐selectin or ELAM‐1), vascular
cell adhesion molecule‐1 (VCAM‐1), and intercellular adhesion molecule‐l (ICAM‐1) is …

NF-KB and the other members of the Rel family of transcriptional activator proteins have been
a focal point for understanding how extracellular signals induce the expression of specific …

Molecular genetics approaches have been used to identify and characterize cis-acting DNA
sequences required for eukaryotic gene regulation. These sequences are modular in nature…

A simple and efficient method for synthesizing pure single stranded RNAs of virtually any
structure is described. This invitro transcription system is based on the unusually specific RNA …

The transcription factors interferon regulatory factor 3 (IRF3) and NF-κB are required for the
expression of many genes involved in the innate immune response. Viral infection, or the …

… genotypes and showed that PHA-driven T cell blasts (PHA-T cells) from patients with AR
or AD … We also showed that PHA-T cells from a patient with AR IFN-α/β receptor 1 (IFNAR1) …

The expansion in the range and use of cloning techniques is reflected in the growth of this
classic manual from 1 to 3 volumes. The comb-bound large print format (with clear illustrations…

The major cell classes of the brain differ in their developmental processes, metabolism,
signaling, and function. To better understand the functions and interactions of the cell types that …

We demonstrate an essential role for the proteasome complex in two proteolytic processes
required for activation of the transcription factor NF-κB. The p105 precursor of the p50 subunit …

Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease with no effective
treatment. We report the results of a moderate-scale sequencing study aimed at increasing the …