The Rosetta software for macromolecular modeling, docking and design is extensively used
in laboratories worldwide. During two decades of development by a community of …

… in vivo (T Kortemme et al., unpublished data). We describe these approaches in the following
sections, and highlight what can be learned from each study towards achieving the goal of …

The computational de novo protein design is increasingly applied to address a number of
key challenges in biomedicine and biological engineering. Successes in expanding …

A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of coronavirus disease 2019 (COVID-19), has …

… Consider a piece of code, P, written to perform some task, T, in some context, C; P's reusability
can be measured as the number of other contexts besides C in which P can perform T. …

The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed hundreds …

Over the past decade, the Rosetta biomolecular modeling suite has informed diverse
biological questions and engineering challenges ranging from interpretation of low-resolution …

Human immunodeficiency virus (HIV) has a small genome and therefore relies heavily on
the host cellular machinery to replicate. Identifying which host proteins and complexes come …

Protein–protein recognition plays a central role in most biological processes. Although the
structures of many protein–protein complexes have been solved in molecular detail, general …

… Qian, CA Rohl, and T. Kortemme. The second computer program used to analyze the
experimental CD data implements a binary search algorithm. It was used to determine the …