… Infection by intracellular pathogens induces primarily a T H 1-dominant response that …
induces a T H 2 response that is associated with resistance to helminths. The T H 1 to T H 2 …

… on the surface of B and T cells. In order to respond to a wide range of potential antigens, B
and T cells rearrange their immunoglobulin and T cell receptor genes to generate over 10 11 …

… Blocking or augmenting TLR function can modify T H 1/T H 2 balance and manipulate a …
activate T cells, together with antigen presentation. CD4 + T cells differentiate into T H 1 or T …

… CpG DNA induces a strong T-helper-1-like inflammatory response 4,5,6,7 . Accumulating …
The in vivo CpG-DNA-mediated T-helper type-1 response was also abolished in TLR9 -/- mice. …

The imidazoquinoline compounds imiquimod and R-848 are low-molecular-weight immune
response modifiers that can induce the synthesis of interferon-α and other cytokines in a …

… Yet, the influenza virus is immunogenic, triggering protective antibody and cytotoxic T
lymphocyte responses in most healthy adults, and vaccines composed of the inactivated virus …

Stimulation of Toll-like receptors (TLRs) triggers activation of a common MyD88-dependent
signaling pathway as well as a MyD88-independent pathway that is unique to TLR3 and …

… We have generated mice with a cell type-specific disinduced T cell proliferation was … PEC
were stimulated with We further analyzed IFN production from T cells of 5-week-old mice, at a …

… TIRAP-deficient mice were healthy and had a normal composition of B and T lymphocytes, …
c CD4 + T cells (H-2 d ) at the indicated concentrations. Proliferative responses of T cells were …

Recognition of pathogens by Toll-like receptors (TLRs) triggers innate immune responses
through signaling pathways mediated by Toll–interleukin 1 receptor (TIR) domain–containing …