User profiles for T. Gaunt

Tom Gaunt

MRC Integrative Epidemiology Unit, University of Bristol
Verified email at bristol.ac.uk
Cited by 35358

Fundamentals of power systems modelling in the presence of converter-interfaced generation

M Paolone, T Gaunt, X Guillaud, M Liserre… - Electric Power Systems …, 2020 - Elsevier
… In (2) we supposed the time window T to contain an integer number of periods 1/f 0 .
However, in power systems voltage or current signals are rarely in steady-state, since they are …

Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary …

…, M Matarin, J Whittaker, TR Gaunt… - International journal …, 2013 - academic.oup.com
Background At the APOE gene, encoding apolipoprotein E, genotypes of the ε2/ε3/ε4 alleles
associated with higher LDL-cholesterol (LDL-C) levels are also associated with higher …

[HTML][HTML] Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis

…, JPT Higgins, M Gardner, C Perks, T Gaunt… - Cancer Causes & …, 2017 - Springer
Purpose To establish whether the association between milk intake and prostate cancer operates
via the insulin-like growth factor (IGF) pathway (including IGF-I, IGF-II, IGFBP-1, IGFBP-2…

The MR-Base platform supports systematic causal inference across the human phenome

…, C Relton, RM Martin, G Davey Smith, TR Gaunt… - elife, 2018 - elifesciences.org
… This has the tremendous advantage that causal inference can be made between two traits
even if they aren’t measured in the same set of samples, enabling us to harness the statistical …

[PDF][PDF] Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

…, M Shivakumar, J Steinberg, H Takuwa, LF Thomas… - Cell, 2021 - cell.com
Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …

Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models

…, GLA Barker, KJ Edwards, INM Day, TR Gaunt - Human …, 2013 - Wiley Online Library
The rate at which nonsynonymous single nucleotide polymorphisms (ns SNP s) are being
identified in the human genome is increasing dramatically owing to advances in whole‐…

Hardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studies

S Rodriguez, TR Gaunt, INM Day - American journal of …, 2009 - academic.oup.com
Mendelian randomization (MR) permits causal inference between exposures and a disease.
It can be compared with randomized controlled trials. Whereas in a randomized controlled …

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

…, M Elkalaawy, K Fischer, OH Franco, TR Gaunt… - Nature, 2017 - nature.com
Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at
risk of developing type 2 diabetes, cardiovascular disease and related metabolic and …

[PDF][PDF] Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

…, C Weikert, H Boeing, S Ebrahim, TR Gaunt… - Bmj, 2014 - bmj.com
… , professor emeritus48 49 50, Cornelia Weikert scientist, group head14, Heiner Boeing
professor and head of department14, Shah Ebrahim professor of public health4, Tom R Gaunt

[PDF][PDF] DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis

…, SE Håberg, Z Xu, JB Van Meurs, TR Gaunt… - The American Journal of …, 2016 - cell.com
Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …