Abstract Changes in DNA methylation in cancer have been heralded as promising targets for
the development of powerful diagnostic, prognostic, and predictive biomarkers. Despite the …

Background It is widely believed that females have longer telomeres than males, although
results from studies have been contradictory. Methods We carried out a systematic review and …

Since the serendipitous discovery 20 years ago of bona fide camelid heavy-chain antibodies,
their single-domain antigen-binding fragments, known as VHHs or nanobodies, have …

… Tim De Meyer … Sofie Bekaert and Tim De Meyer were funded by grants from the
Special Research Fund of Ghent University (grant 01109502 and 011D10004, respectively). …

As with every -omics technology, metabolomics requires new methodologies for data
processing. Due to the large spectral size, a standard approach in NMR-based metabolomics …

… Tim De Meyer … This work was supported by grants from the Vlaamse Liga tegen
Kanker (VLK) and the Fonds de la Recherche Scientifique (FNRS). … Tim De Meyer …

Thyroid dysfunction is an important public health problem, which affects 10% of the general
population and increases the risk of cardiovascular morbidity and mortality. Many aspects of …

Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are
derived almost exclusively from small and polyadenylated RNAs. Here we present a more …

Although evidence supports the function of telomere length (TL) as a marker for biological
aging, no major determinants of TL are known besides inheritance, age and gender. Here we …

Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population.
Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of …