Over 600 million years ago, animals evolved from a unicellular or colonial organism whose
cell(s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar collar. …

The textbook view of cell division terminates with the final separation of the two daughter
cells in the process called abscission. However, in contrast to this classical view, a variety of …

Eukaryotic cells convert external stimuli into membrane depolarization, which in turn triggers
effector responses such as secretion and contraction. Here, we put forward an evolutionary …

… To demonstrate the separability of syndromes with facial dysmorphism, we also used t-SNE
to project 4,353 images of the ten syndromes from the frequent set with the largest number of …

… Because all the oscillations shift as a whole, we focus our attention on the centre of the
pulses, denoted by t phase and for which the amplitude is zero, as depicted in Fig. 2b–d. …

Background Dystonia is a clinically and genetically heterogeneous condition that occurs in
isolation (isolated dystonia), in combination with other movement disorders (combined …

The modulation of developmental biochemical pathways by mechanical cues is an emerging
feature of animal development, but its evolutionary origins have not been explored. Here …

A critical step in preserving protein homeostasis is the recognition, binding, unfolding, and
translocation of protein substrates by six AAA-ATPase proteasome subunits (ATPase-…

Collective cell contractions that generate global tissue deformations are a signature feature
of animal movement and morphogenesis. However, the origin of collective contractility in …

Resonance phenomena occur with all types of vibrations or waves and may play a part in
spectacular events, such as the collapse of structures—for example, the fall of the Broughton …