Plants have an extraordinary diversity of transcription machineries, including five nuclear
DNA-dependent RNA polymerases. Four of these enzymes are dedicated to the production of …

Dulaglutide (DU) is a once weekly glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA)
approved for the treatment of type 2 diabetes mellitus (T2DM). Glycaemic efficacy and safety …

… For a data sequence {x t }, at one time point t=0, we can obtain 2M+1 samples centered
at t, which can be used to fit the following k-th order polynomial with a minimized residual: …

Background Liraglutide 3·0 mg was shown to reduce bodyweight and improve glucose
metabolism after the 56-week period of this trial, one of four trials in the SCALE programme. In …

Synthetic peptide analogues of sequences in the HER-2 protooncogene (HER-2) were
selected based on the presence of HLA-A2.1 anchor motifs to identify the epitopes on HER-2 …

… To determine the relative contribution of these pathways, we examined the effect of well-characterized,
T-DNA insertion deficiency mutants on the infection process, VIGS, and the …

The latest update to Bela Liptak's acclaimed "bible" of instrument engineering is now available.
Retaining the format that made the previous editions bestsellers in their own right, the …

Background Obesity is a major risk factor for many leading causes of illness and death
worldwide. Data are needed regarding the efficacy and safety of the nonpeptide glucagon-like …

Context: We wanted to understand the effects of once-weekly vs. twice-daily glucagon-like
peptide-1 receptor agonism for treatment of patients with type 2 diabetes. Objective: The …

Epigenetic states and certain environmental responses in mammals and seed plants can
persist in the next sexual generation. These transgenerational effects have potential adaptative …