User profiles for T. P. Speed

Terence P Speed

Walter & Eliza Hall Institute of Medical Research
Verified email at wehi.edu.au
Cited by 111645

Comparison of methods for image analysis on cDNA microarray data

…, MJ Buckley, S Dudoit, TP Speed - Journal of computational …, 2002 - Taylor & Francis
Microarrays are part of a new class of biotechnologies which allow the monitoring of expression
levels for thousands of genes simultaneously. Image analysis is an important aspect of …

Regulation of apicomplexan actin-based motility

J Baum, AT Papenfuss, B Baum, TP Speed… - Nature Reviews …, 2006 - nature.com
… They are able to move at great speeds 5 but do so in the absence of actin-based structures
(for example, lamellapodia or filopodia) or microtubular-based structures (for example, cilia …

Analysis of cDNA microarray images

YH Yang, MJ Buckley, TP Speed - Briefings in bioinformatics, 2001 - academic.oup.com
Microarrays are part of a new class of biotechnologies that allow the monitoring of expression
levels for thousands of genes simultaneously. Image analysis is an important aspect of …

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

…, KJ Antonellis, U Scherf, TP Speed - …, 2003 - academic.oup.com
In this paper we report exploratory analyses of high‐density oligonucleotide array data from
the Affymetrix GeneChip ® system with the objective of improving upon currently used …

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

BM Bolstad, RA Irizarry, M Åstrand, TP Speed - Bioinformatics, 2003 - academic.oup.com
… This paper uses invariants sets since it increases the implementation speed. To deal with
more than two arrays, the method is extended to look at all distinct pairwise combinations. The …

[PDF][PDF] Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

…, A Kahn, PT Spellman, RK Wilson, TP Speed… - Cancer cell, 2010 - cell.com
The Cancer Genome Atlas Network recently cataloged recurrent genomic abnormalities in
glioblastoma multiforme (GBM). We describe a robust gene expression-based molecular …

Summaries of Affymetrix GeneChip probe level data

…, F Collin, LM Cope, B Hobbs, TP Speed - Nucleic acids …, 2003 - academic.oup.com
High density oligonucleotide array technology is widely used in many areas of biomedical
research for quantitative and highly parallel measurements of gene expression. Affymetrix …

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

…, P Luu, DM Lin, V Peng, J Ngai, TP Speed - Nucleic acids …, 2002 - academic.oup.com
There are many sources of systematic variation in cDNA microarray experiments which affect
the measured gene expression levels (eg differences in labeling efficiency between the …

Comparison of discrimination methods for the classification of tumors using gene expression data

S Dudoit, J Fridlyand, TP Speed - Journal of the American …, 2002 - Taylor & Francis
A reliable and precise classification of tumors is essential for successful diagnosis and
treatment of cancer. cDNA microarrays and high-density oligonucleotide chips are novel …

On the application of probability theory to agricultural experiments. Essay on principles. Section 9.

J Splawa-Neyman, DM Dabrowska, TP Speed - Statistical Science, 1990 - JSTOR
… Dorota Dabrowska and Terry Speed are to be most warmly thanked for bringing this
fundamentally important but previously recondite early work of Jerzy Neyman to the attention of the …