Embryonic stem cells have the ability to remain undifferentiated and proliferate indefinitely
in vitro while maintaining the potential to differentiate into derivatives of all three embryonic …

We report the derivation of eight pluripotent cell lines from common marmoset (Callithrix
jacchus) blastocysts. These cell lines are positive for a series of markers (alkaline phosphatase, …

The transcriptional regulation of neuroectoderm (NE) specification is unknown. Here we
show that Pax6 is uniformly expressed in early NE cells of human fetuses and those …

Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …

Trophoblast differentiation and early placental development are essential for the establishment
of pregnancy, yet these critical events are not readily investigated in human pregnancy. …

In the preimplantation mouse embryo, TEAD4 is critical to establishing the trophectoderm (TE)-specific
transcriptional program and segregating TE from the inner cell mass (ICM). …

Background Zika virus (ZIKV; Flaviviridae, Flavivirus) was declared a public health emergency
of international concern by the World Health Organization (WHO) in February 2016, …

… TG assisted with non-human primate studies, and contributed to the writing of the manuscript…
Copyright © 2018 Reyes and Golos. This is an open-access article distributed under the …

In response to the outbreak of Zika virus (ZIKV) infection in the Western Hemisphere and the
recognition of a causal association with fetal malformations, the Global Virus Network (GVN) …