User profiles for T. D. Dyer

Thomas Dyer

University of Dundee
Verified email at dundee.ac.uk
Cited by 1199

[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

…, H Dong, G Donohoe, R Duggirala, TD Dyer… - Brain imaging and …, 2014 - Springer
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …

Common genetic variants influence human subcortical brain structures

…, GI De Zubicaray, A Dillman, R Duggirala, TD Dyer… - Nature, 2015 - nature.com
The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …

Identification of common variants associated with human hippocampal and intracranial volumes

…, N Delanty, C Depondt, R Duggirala, TD Dyer… - Nature …, 2012 - nature.com
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes

HHH Göring, JE Curran, MP Johnson, TD Dyer… - Nature …, 2007 - nature.com
Quantitative differences in gene expression are thought to contribute to phenotypic differences
between individuals. We generated genome-wide transcriptional profiles of lymphocyte …

[PDF][PDF] Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans

R Duggirala, J Blangero, L Almasy, TD Dyer… - The American Journal of …, 1999 - cell.com
Since little is known about chromosomal locations harboring type 2 diabetes–susceptibility
genes, we conducted a genomewide scan for such genes in a Mexican American population. …

Genetic variation in selenoprotein S influences inflammatory response

…, G Cai, MC Mahaney, AG Comuzzie, TD Dyer… - Nature …, 2005 - nature.com
Chronic inflammation has a pathological role in many common diseases and is influenced
by both genetic and environmental factors. Here we assess the role of genetic variation in …

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

…, L Almasy, BD Mitchell, MC Mahaney, TD Dyer… - Nature …, 1997 - nature.com
Obesity is a major predisposing factor for the development of several chronic diseases
including non-insulin dependent diabetes mellitus (NIDDM) and coronary heart disease (CHD). …

Chloride binding in GGBS concrete

RK Dhir, MAK El-Mohr, TD Dyer - Cement and Concrete Research, 1996 - Elsevier
This paper reports the results of chloride binding measurements of GGBS pastes, as well as
chloride diffusion and permeability measurements of GGBS concrete mixes. Chloride …

Bivariate quantitative trait linkage analysis: Pleiotropy versus co‐incident linkages

L Almasy, TD Dyer, J Blangero - Genetic epidemiology, 1997 - Wiley Online Library
Power to detect linkage and localization of a major gene were compared in univariate and
bivariate variance components linkage analysis of three related quantitative traits in general …

A kernel of truth: statistical advances in polygenic variance component models for complex human pedigrees

J Blangero, VP Diego, TD Dyer, M Almeida, J Peralta… - Advances in …, 2013 - Elsevier
Statistical genetic analysis of quantitative traits in large pedigrees is a formidable computational
task due to the necessity of taking the nonindependence among relatives into account. …