The microbial community of the human gut has a crucial role in sustaining host homeostasis.
High-throughput DNA sequencing has delineated the structural and functional …

Background Huntington’s disease (HD) is an incurable hereditary neurodegenerative disorder,
which manifests itself as a loss of GABAergic medium spiny (GABA MS) neurons in the …

Yield of protein per translated mRNA may vary by four orders of magnitude. Many studies
analyzed the influence of mRNA features on the translation yield. However, a detailed …

The avian bacterial pathogen Mycoplasma gallisepticum is a good model for systems studies
due to small genome and simplicity of regulatory pathways. In this study, we used RNA-…

Translation efficiency contributes several orders of magnitude difference in the overall yield
of exogenous gene expression in bacteria. In diverse bacteria, the translation initiation site, …

Background Human hepatoma HepG2 cells are used as an in vitro model of the human liver.
High-throughput transcriptomic sequencing is an advanced approach for assessing the …

Background Protein degradation is a basic cell process that operates in general protein
turnover or to produce bioactive peptides. However, very little is known about the qualitative and …

The major storage proteins in cereals, prolamins, have an abundance of the amino acids
glutamine and proline. Storage pests need specific digestive enzymes to efficiently hydrolyze …

Background Crohn’s disease is associated with gut dysbiosis. Independent studies have
shown an increase in the abundance of certain bacterial species, particularly Escherichia coli …

Background Escherichia coli (E. coli) has been increasingly implicated in the pathogenesis
of Crohn’s disease (CD). The phylogeny of E. coli isolated from Crohn’s disease patients (…