… a transcriptional landscape that is transmitted from a cell to its progeny (Citation19). Even
though the epigenetic state is essentially stable throughout cell generations, it is far from static. …

The three-spined stickleback (Gasterosteus aculeatus) represents a convenient model to study
microevolution—adaptation to a freshwater environment. Although genetic adaptations to …

DNA methylation is the most important epigenetic modification involved in the regulation of
transcription, imprinting, establishment of X-inactivation, and the formation of a chromatin …

Gain and loss of DNA methylation in cells is a dynamic process that tends to achieve an
equilibrium. Many factors are involved in maintaining the balance between DNA methylation …

… biological significance of Kaiso SUMOylation is unclear. Here, we find that K42 is the only
amino acid within Kaiso that is modified with SUMO. Kaiso is monoSUMOylated at lysine 42 in …

Secretion of mildly alkaline (pH 8.0–8.5) juice to intestines is one of the key functions of the
pancreas. Recent reports indicate that the pancreatic duct system containing the alkaline …

Kaiso is a methyl DNA binding transcriptional factor involved in cell cycle control, WNT signaling,
colon inflammation, and cancer progression. Recently, it was shown that SUMOylation …

The ubiquitously expressed transcription factor Oct-1 is a member of the POU protein family.
It is involved in the activation of snRNA promoters and some mRNA promoters (eg, …

… Here, we provide evidence that Kaiso’s effects on intestinal secretory cell fates precede
the development of intestinal inflammation in Kaiso Tg mice. We also demonstrate that Kaiso …

… In plants, genomic imprinting is characteristic of endosperm tissue; in insects, it is involved
in the elimination of the paternal X chromosome [1, 2]. In mammals, genomic imprinting is …