Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation

S Millevoi, S Vagner - Nucleic acids research, 2010 - academic.oup.com
Messenger RNA (mRNA) 3′ end formation is a nuclear process through which all eukaryotic
primary transcripts are endonucleolytically cleaved and most of them acquire a poly(A) tail. …

Generation of protein isoform diversity by alternative initiation of translation at non‐AUG codons

…, S Audigier, H Prats, AC Prats, S Vagner - Biology of the …, 2003 - Wiley Online Library
… , such as “leaky scanning”, or that are exception to this rule, such as internal entry of
ribosomes, have been proposed to account for the selection of the internal initiation codon(s). …

G‐quadruplexes in RNA biology

S Millevoi, H Moine, S Vagner - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
G‐quadruplexes are noncanonical structures formed by G‐rich DNA and RNA sequences
that fold into a four‐stranded conformation. Experimental studies and computational …

Reversible and adaptive resistance to BRAF (V600E) inhibition in melanoma

…, S Hobor, PK Bajpe, C Lieftink, C Mateus, S Vagner… - Nature, 2014 - nature.com
… To identify which gene(s) in the chromatin regulator library when suppressed can induce
EGFR … We thank S. Roy for collecting clinical data and N. Kamsu Kom for tissue preparation. …

eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies

…, AM Eggermont, L Desaubry, C Robert, S Vagner - Nature, 2014 - nature.com
… Cells were then pulsed for 30 min with [ 35 S]Cys/Met, and the incorporation of 35 S into
proteins was quantified and normalized to the total protein amount. The data are presented as …

The multiple roles of LDH in cancer

…, V Quidville, F Chehade, S Shen, S Vagner… - Nature Reviews …, 2022 - nature.com
High serum lactate dehydrogenase (LDH) levels are typically associated with a poor
prognosis in many cancer types. Even the most effective drugs, which have radically improved …

Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth

…, H Roché, F Dalenc, D Auboeuf, S Millevoi, S Vagner - Cancer research, 2009 - AACR
… Grant support: Institut National de la Sante et de la Recherche Medicale, Institut Claudius
Regaud and FRM (Equipe FRM, soutenue par la Fondation Recherche Médicale; S. Vagner). …

[HTML][HTML] Alternative translation of the proto-oncogene c-mycby an internal ribosome entry site

…, I Lafon, S Audigier, MC Gensac, S Vagner… - Journal of Biological …, 1997 - ASBMB
… Capped and uncapped mRNAs were transcribed in vitro and translated in RRL in the
presence of [ 35 S]methionine. Their translation efficiencies were compared (Fig. 1, B and C). …

[PDF][PDF] Persistent cancer cells: the deadly survivors

S Shen, S Vagner, C Robert - Cell, 2020 - cell.com
… patient’s body until they eventually give rise to clinical progression. As such, cancer cell
persistence appears to be the most challenging obstacle to effective and durable anticancer treat…

Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes

S Vagner, MC Gensac, A Maret, F Bayard… - … and cellular biology, 1995 - Am Soc Microbiol
… Capped or uncapped RNAs were generated in vitro by T7 or T3 RNA polymerase
according to the manufacturer’s instructions, with or without adding m7GpppG (0.5 mM) to the …