User profiles for S. Rizzetto

Simone Rizzetto

Genome Institute of Singapore
Verified email at gis.a-star.edu.sg
Cited by 1208

[HTML][HTML] Mass cytometry for the assessment of immune reconstitution after hematopoietic stem cell transplantation

L Stern, H McGuire, S Avdic, S Rizzetto… - Frontiers in …, 2018 - frontiersin.org
… High computational speeds are achieved in FlowSOM without the requirement for down-sampling,
contributing to FlowSOM’s ability to detect phenotypically rare cell populations hidden …

[HTML][HTML] Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

…, S Rizzetto, AA Eltahla, EB Clemens, S Sant… - Nature …, 2019 - nature.com
… Lung samples were obtained via the Alfred Hospital’s Lung Tissue Biobank from individuals
who did not die of immunological conditions or influenza infection. Tonsils were obtained …

[PDF][PDF] A liver capsular network of monocyte-derived macrophages restricts hepatic dissemination of intraperitoneal bacteria by neutrophil recruitment

F Sierro, M Evrard, S Rizzetto, M Melino, AJ Mitchell… - Immunity, 2017 - cell.com
… LCM proliferation was assessed both during the weaning phase and in adults using FUCCI
transgenic mice that allow determination of cells in G1 and/or S/G2/M phases of the cell cycle …

[HTML][HTML] Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease

…, JC Crawford, AA Eltahla, S Rizzetto… - Nature …, 2018 - nature.com
… Standard two-tail Student’s t-test was performed with p value as indicated … These results
imply that a patient’s recovery is associated with the early clonal expansion of a few “optimal” (…

Cytotoxic T cells swarm by homotypic chemokine signalling

…, MA Govendir, LF Dagley, K Hsu, S Rizzetto… - Elife, 2020 - elifesciences.org
Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search
or following signals by other leukocytes. Here, we reveal independent emergent behaviour …

Linking the T cell receptor to the single cell transcriptome in antigen‐specific human T cells

AA Eltahla, S Rizzetto, MR Pirozyan… - Immunology and cell …, 2016 - Wiley Online Library
… The PCR conditions were 95 C for 2 min, followed by 35 cycles od 95 C for 20 s, 52 C for
20 s, and 72 C for 45 s, the final extension was performed at 72 C for 7 min. PCR cleanup was …

B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle

S Rizzetto, DNP Koppstein, J Samir, M Singh… - …, 2018 - academic.oup.com
Motivation The B-cell receptor (BCR) performs essential functions for the adaptive immune
system including recognition of pathogen-derived antigens. The vast repertoire and adaptive …

[PDF][PDF] Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody

…, D Koppstein, TJ Peters, DL Burnett, S Rizzetto… - Cell, 2020 - cell.com
… Having used the RNA to identify single, clonally related rogue cells responsible for each
patient’s autoantibody and also polyclonal control memory B cells in the same blood sample, …

Pan-cancer analysis of ligand–receptor cross-talk in the tumor microenvironment

…, E Revkov, YA Guo, S Rizzetto, AML Wong, S Solai… - Cancer research, 2021 - AACR
… This yields a stroma-to-cancer (S>C) RC score of 60%. D, Median RC score across the
20 solid tumor types was estimated and plotted for each direction of signaling. E and F, RC …

[HTML][HTML] Impact of sequencing depth and read length on single cell RNA sequencing data of T cells

S Rizzetto, AA Eltahla, P Lin, R Bull, AR Lloyd… - Scientific reports, 2017 - nature.com
… credit to the original author(s) and the source, provide a … ’s Creative Commons license,
unless indicated otherwise in a credit line to the material. If material is not included in the article’s