User profiles for S. Röh

Simone Röh-Karamihalev, Dr.rer.nat.

Bioinformatician, Max Planck Institute of Psychiatry
Verified email at r-post.de
Cited by 2242

[HTML][HTML] Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling

AS Zannas, J Arloth, T Carrillo-Roa, S Iurato, S Röh… - Genome biology, 2015 - Springer
Background Chronic psychological stress is associated with accelerated aging and increased
risk for aging-related diseases, but the underlying molecular mechanisms are unclear. …

[PDF][PDF] The role of m6A/m-RNA methylation in stress response regulation

M Engel, C Eggert, PM Kaplick, M Eder, S Röh, L Tietze… - Neuron, 2018 - cell.com
… In this study, we aimed to elucidate the role of m6A/m in the context of the brain’s stress
response. We delineated the effects of acute stress on m6A/m using global m6A/m …

[HTML][HTML] Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis

…, ST Liffers, S Oeljeklaus, K Kuhlmann, S Röh… - Molecular & Cellular …, 2011 - ASBMB
… ), which encode factors required for G 1 /S transition (c-MYC, E2F, CDK4, CDK6), anti-apoptotic …
of previously selected precursor ions was dynamically excluded for the following 45 s. …

Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk

…, S Martinelli, M Roitman, S Röh… - Proceedings of the …, 2019 - National Acad Sciences
Aging and psychosocial stress are associated with increased inflammation and disease risk,
but the underlying molecular mechanisms are unclear. Because both aging and stress are …

Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

…, N Cattane, T Wiechmann, S Röh… - Proceedings of the …, 2020 - National Acad Sciences
Prenatal stress exposure is associated with risk for psychiatric disorders later in life. This may
be mediated in part via enhanced exposure to glucocorticoids (GCs), which are known to …

AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer

R Jackstadt, S Röh, J Neumann, P Jung… - Journal of Experimental …, 2013 - rupress.org
… CRC specimens from patients that underwent curative surgical resection between 1994
and 2005 at the LMU were drawn from the Institute’s archives, assuring that a 6-yr follow-up …

High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders

…, E Kaya, AC Krontira, S Röh… - Proceedings of the …, 2023 - National Acad Sciences
… for psychiatric disorders by altering an individual’s physiological stress response set-point. …
Science is among humanity’s greatest achievements, yet scientific censorship is rarely …

[HTML][HTML] Re-annotator: annotation pipeline for microarray probe sequences

J Arloth, DM Bader, S Röh, A Altmann - PloS one, 2015 - journals.plos.org
… We applied Re-Annotator to the Illumina Human-HT12 v4 microarray platform and found
that about one quarter (25%) of the probes differed from the manufacturer’s annotation. In …

[HTML][HTML] Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus

T Wiechmann, S Röh, S Sauer, D Czamara, J Arloth… - Clinical …, 2019 - Springer
… as CpGs differentially methylated in Cushing’s syndrome patients, a disorder characterized
… active Cushing’s syndrome and controls but also in patients with cured Cushing’s syndrome […

The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1

…, R Malik, B Lindner, N Ziesch, M Rex-Haffner, S Röh… - Stroke, 2019 - Am Heart Assoc
… Since E2F3 and Rb1 control cell cycle progression at the G1/S boundary, 23 we arrested
these cells with hydroxyurea. On synchronization, we found a significantly enriched occupancy …