Fiji is a distribution of the popular open-source software ImageJ focused on biological-image
analysis. Fiji uses modern software engineering practices to combine powerful software …

Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only fluorophores
within the focal volume. Light sheet microscopes (LSMs) have a true optical sectioning …

Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as a …

Motivation: Modern anatomical and developmental studies often require high-resolution
imaging of large specimens in three dimensions (3D). Confocal microscopy produces high-…

… Indeed, ever since Schwann’s theory of the cell and Cajal’s neuron doctrine, neuroscientists
have struggled to describe the diversity of neurons in the brain and their synaptic contacts …

To the Editor: Selective plane illumination microscopy (SPIM) 1 allows isotropic, time-lapse,
in toto imaging of large, living biological specimens by acquiring three-dimensional (3D) …

The analysis of microcircuitry (the connectivity at the level of individual neuronal processes
and synapses), which is indispensable for our understanding of brain function, is based on …

… To discover the functional classes of genes responsible for driving the hourglass pattern
in the data, we correlated each gene’s divergence profile with the average across all genes, …

… ) for the Csp-sGFP transgene, and S. Singh, Sonal and S. Simmert for seeding the wiki with
… algorithm and fused using multiview deconvolution (Preibisch et al., unpublished data) for 12 …

In addition, ClearVolume can be used for aligning and calibrating light-sheet microscopes.
The overall 3D point spread function of the optical system and the full 3D structure of the …