Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
Although genomewide RNA expression analysis has become a routine tool in biomedical
research, extracting biological insight from such information remains a major challenge. Here, …
research, extracting biological insight from such information remains a major challenge. Here, …
[HTML][HTML] A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
[HTML][HTML] Swarm learning for decentralized and confidential clinical machine learning
…, H Schultze, KL Shastry, S Manamohan, S Mukherjee… - Nature, 2021 - nature.com
Fast and reliable detection of patients with severe and heterogeneous illnesses is a major
goal of precision medicine 1 , 2 . Patients with leukaemia can be identified using machine …
goal of precision medicine 1 , 2 . Patients with leukaemia can be identified using machine …
Asymmetric enamine catalysis
S Mukherjee, JW Yang, S Hoffmann, B List - Chemical Reviews, 2007 - ACS Publications
The catalysis by primary and secondary amines of electrophilic substitution reactions in the
R-position of carbonyl compounds and related reactions via enamine intermediates is called …
R-position of carbonyl compounds and related reactions via enamine intermediates is called …
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
…, BD Mitchell, MA Morken, S Mukherjee, S Naitza… - Nature …, 2010 - nature.com
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
Prediction of central nervous system embryonal tumour outcome based on gene expression
…, C Wetmore, JA Biegel, T Poggio, S Mukherjee… - Nature, 2002 - nature.com
Embryonal tumours of the central nervous system (CNS) represent a heterogeneous group
of tumours about which little is known biologically, and whose diagnosis, on the basis of …
of tumours about which little is known biologically, and whose diagnosis, on the basis of …
Multiclass cancer diagnosis using tumor gene expression signatures
The optimal treatment of patients with cancer depends on establishing accurate diagnoses by
using a complex combination of clinical and histopathological data. In some instances, this …
using a complex combination of clinical and histopathological data. In some instances, this …
Metal–organic frameworks: functional luminescent and photonic materials for sensing applications
… S 0 to the donor S 0 , followed by phosphorescence on the acceptor. (c) Mechanism of
photoinduced electron transfer (PET), with the donor excited state reducing the acceptor, resulting …
photoinduced electron transfer (PET), with the donor excited state reducing the acceptor, resulting …
[HTML][HTML] Cosmology intertwined: A review of the particle physics, astrophysics, and cosmology associated with the cosmological tensions and anomalies
The standard Λ Cold Dark Matter (ΛCDM) cosmological model provides a good description
of a wide range of astrophysical and cosmological data. However, there are a few big open …
of a wide range of astrophysical and cosmological data. However, there are a few big open …
[HTML][HTML] Abiraterone in metastatic prostate cancer without previous chemotherapy
…, H Van Poppel, SD Mukherjee… - … England Journal of …, 2013 - Mass Medical Soc
Background Abiraterone acetate, an androgen biosynthesis inhibitor, improves overall
survival in patients with metastatic castration-resistant prostate cancer after chemotherapy. We …
survival in patients with metastatic castration-resistant prostate cancer after chemotherapy. We …